1-Phenazinecarboxylic acid methyl ester

Base Information

• Chemical Name: 1-Phenazinecarboxylic acid methyl ester
• CAS No.: 3225-19-2
• Molecular Formula: C14H10N2O2
• Molecular Weight: 238.246
• Hs Code.: 2933990090
• Mol file: 3225-19-2.mol

Synonyms:1-methoxycarbonylphenazine;phenazine-1-carboxylic acid methyl ester;Phenazin-1-carbonsaeure-methylester;1-carbomethoxy-phenazine;Methyl 1-phenazinecarboxylate;1-Phenazinecarboxylic acid,methyl ester;

Chemical Property of 1-Phenazinecarboxylic acid methyl ester

Chemical Property:

• PSA: 52.08000
• LogP: 2.56960

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Phenazinecarboxylic acid methyl ester

There total 12 articles about 1-Phenazinecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.1%

methanol (67-56-1) + phenazine-1-carboxylic acid chloride → phenazine-1-carboxylic acid methyl ester (3225-19-2)

Guidance literature:

With oxalyl dichloride; at 0 - 5 ℃; for 0.5h;

Reference yield: 86.0%

methanol (67-56-1) + tubermycin B (2538-68-3,102646-59-3) → phenazine-1-carboxylic acid methyl ester (3225-19-2)

Guidance literature:

With sulfuric acid;

Reference yield: 37.0%

methyl 3-(1,3-dihydro-2H-benzo[d][1,3,2]diazaborol-2-yl)benzoate → methyl phenazine-2-carboxylate (18450-12-9) + phenazine-1-carboxylic acid methyl ester (3225-19-2)

Guidance literature:

With silver(l) oxide; In dimethyl sulfoxide; at 80 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1039/d1cc06705b

upstream raw materials:

diazomethane

tubermycin B

methanol

anthranilic acid

Downstream raw materials:

phenazine-1-carboxamide

1-methyl-phenazine

Refernces

• 1、 Puopolo, Gerardo,Masi, Marco,Raio, Aida,Andolfi, Anna,Zoina, Astolfo,Cimmino, Alessio,Evidente, Antonio. "Insights on the susceptibility of plant pathogenic fungi to phenazine-1-carboxylic acid and its chemical derivatives". . p. 956 - 966. Retrieved 2013.
• 2、 Zhu, Xiang,Zhang, Min,Yu, Linhua,Xu, Zhihong,Yang, Dan,Du, Xiaoying,Wu, Qinglai,Li, Junkai. "Synthesis and bioactivities of diamide derivatives containing a phenazine-1-carboxamide scaffold". . p. 2453 - 2460. Retrieved 2018/03/29.