Technology Process of 12,13-Epoxy-11-oxo-9-octadecenoic acid
There total 4 articles about 12,13-Epoxy-11-oxo-9-octadecenoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Porcine pancreas lipase type II;
In
aq. phosphate buffer; acetone;
at 20 ℃;
for 4h;
pH=7;
Inert atmosphere;
Enzymatic reaction;
DOI:10.1039/d1cc02475b
- Guidance literature:
-
With
lithium hydroxide;
In
isopropyl alcohol;
at 24 - 26 ℃;
for 1h;
DOI:10.1021/jo701373f
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ozone / methanol; dichloromethane / -78 °C / Inert atmosphere
1.2: 0.5 h / Inert atmosphere
2.1: toluene / 48 h / Reflux; Inert atmosphere
3.1: Porcine pancreas lipase type II / acetone; aq. phosphate buffer / 4 h / 20 °C / pH 7 / Inert atmosphere; Enzymatic reaction
With
Porcine pancreas lipase type II; ozone;
In
methanol; aq. phosphate buffer; dichloromethane; acetone; toluene;
2.1: |Wittig Olefination;
DOI:10.1039/d1cc02475b
