9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate

Base Information

• Chemical Name: 9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate
• CAS No.: 5132-82-1
• Molecular Formula: C17H18NO6S+
• Molecular Weight: 0
• Hs Code.: 2933990090
• Mol file: 5132-82-1.mol

Synonyms:9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate;9-Carboxy-10-methylacridinium Methyl Sulfate Methyl Ester;NSC 147446

Chemical Property of 9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 104.99000
• Density: g/cm³
• LogP: 2.77790
• Solubility.: Methanol

Purity/Quality:

99% ^*data from raw suppliers

9-(Methoxycarbonyl)-10-methylacridiniumMethylSulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate (cas# 5132-82-1) is a compound useful in organic synthesis.

Technology Process of 9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate

There total 4 articles about 9-(Methoxycarbonyl)-10-methylacridinium Methyl Sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl acridine-9-carboxylate (5132-81-0) + dimethyl sulfate (77-78-1) → 9-[(carbonyl)methoxy]-10-methylacridinium methylsulfate (5132-82-1)

Guidance literature:

Reference yield:

1-phenyl-indole-2,3-dione (723-89-7) → 9-[(carbonyl)methoxy]-10-methylacridinium methylsulfate (5132-82-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / NaOH / H₂O / 18 h / Heating

2: 95 percent / CH₂Cl₂ / 0.25 h / 0 °C

3: 98 percent

With sodium hydroxide; In dichloromethane; water;

Reference yield:

acridine-9-carboxylic acid (5336-90-3) → 9-[(carbonyl)methoxy]-10-methylacridinium methylsulfate (5132-82-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / SOCl₂

2: 86 percent

3: 89 percent

With thionyl chloride;

DOI:10.1016/S0040-4039(00)61545-9

upstream raw materials:

methyl acridine-9-carboxylate

dimethyl sulfate

acridine-9-carboxylic acid

9-acridinecarbonyl chloride

Downstream raw materials:

9-ethoxycarbonyl-10-methylacridane

9-Bromomethyl-10-methyl-9,10-dihydro-acridine-9-carboxylic acid ethyl ester

N-methyldibenzazepine

Refernces

• 1、 Zheng, Zhizhen Barbara,Dowd, Paul. "A Free Radical Route to the Benzazepines and Dibenzazepines". . p. 7709 - 7712. Retrieved 2007/10/02.