Diethyl cromoglycate

Base Information Edit

Chemical Name:Diethyl cromoglycate
CAS No.:16150-45-1
Molecular Formula:C27H24O11
Molecular Weight:524.481
Hs Code.:
European Community (EC) Number:605-256-2
UNII:SMU3BJ0QSN
DSSTox Substance ID:DTXSID20167164
Nikkaji Number:J493.408C
Wikidata:Q72469232
Mol file:16150-45-1.mol

Synonyms:Diethyl cromoglycate;16150-45-1;Cromophene;Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate);Cromoglycic acid diethyl ester;ethyl 5-[3-(2-ethoxycarbonyl-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate;SMU3BJ0QSN;BRN 1337752;Ethyl Cromoglicate;C27H24O11;EC 605-256-2;4H-1-Benzopyran-2-carboxylic, 5,5'-((2-hydroxytrimethylene)dioxy)bis(4-oxo-, diethyl ester;Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)-bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate);4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo-, diethyl ester;4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo) diethyl ester;Diethyl 5,5'-[(2-hydroxypropane-1,3-diyl)dioxy]bis(4-oxo-4H-1-benzopyran-2-carboxylate) (Ethyl Cromoglicate);4H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 5,5'-((2-HYDROXY-1,3-PROPANEDIYL)BIS(OXY))BIS(4-OXO-, 2,2'-DIETHYL ESTER;4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-, 2,2'-diethyl ester;UNII-SMU3BJ0QSN;SCHEMBL143979;1,3-Bis(2-ethoxycarbonylchromon-5-yloxy)-2-hydroxypropan;DTXSID20167164;AC-126;MFCD01762791;AKOS015963154;C27-H24-O11;AS-15223;LS-39175;CS-0151767;FT-0649063;D94547;CROMOLYN RELATED COMPOUND B [USP IMPURITY];SODIUM CROMOGLICATE IMPURITY B [EP IMPURITY];5,5'-(2-Hydroxytrimethylenebisoxy)bis(4-oxo-4H-1-benzopyran-2-carboxylic acid ethyl) ester;diethyl 5,5'-(2-hydroxypropane-1,3-diyl)bis(oxy)bis(4-oxo-4H-chromene-2-carboxylate);Diethyl5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate);5,5'-[(2-hydroxytrimethylene)dioxy]bis [4-oxo-4H-1-benzopyran-2-carboxylic acid] diethyl ester;Diethyl 5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylate), Diethyl cromoglycate

Suppliers and Price of Diethyl cromoglycate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DiethylCromoglycate
1g
$ 545.00

Matrix Scientific
Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)-bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) 95+%
250mg
$ 234.00

Matrix Scientific
Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)-bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) 95+%
500mg
$ 359.00

Matrix Scientific
Diethyl 5,5'-((2-hydroxypropane-1,3-diyl)-bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) 95+%
1g
$ 553.00

Crysdot
Diethyl5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) 97%
1g
$ 550.00

Chemenu
Diethyl5,5''-((2-hydroxypropane-1,3-diyl)-bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) 97%
1g
$ 519.00

Biosynth Carbosynth
Diethyl crOmOglycate
250 mg
$ 500.00

Biosynth Carbosynth
Diethyl crOmOglycate
25 mg
$ 100.00

Biosynth Carbosynth
Diethyl crOmOglycate
10 mg
$ 65.00

Biosynth Carbosynth
Diethyl crOmOglycate
50 mg
$ 150.00

Total 55 raw suppliers

Chemical Property of Diethyl cromoglycate Edit

Chemical Property:

Vapor Pressure:1.82E-21mmHg at 25°C
Melting Point:180-182 °C(Solv: ethanol (64-17-5); benzene (71-43-2))
Refractive Index:1.604
Boiling Point:715.175 °C at 760 mmHg
PKA:13.02±0.20(Predicted)
Flash Point:239.049 °C
PSA：151.71000
Density:1.409 g/cm³
LogP:3.07150
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:12
Exact Mass:524.13186158
Heavy Atom Count:38
Complexity:894

Purity/Quality:

99% ^*data from raw suppliers

DiethylCromoglycate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=O)C2=C(O1)C=CC=C2OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)OCC)O
Uses Diethyl cromoglycate is a derivative of Sodium cromoglycate (C815000). Sodium cromoglycate is a bischromone derivative that is used as prophylactic treatment and maintenance of bronchial asthma by preventing the release of histamine in the body.

Technology Process of Diethyl cromoglycate

There total 6 articles about Diethyl cromoglycate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.4%