96-21-9

Basic information

• Product Name: 1,3-Dibromo-2-propanol
• Synonyms: 1,3-Dibromo-2-hydroxypropane;1,3-dibromo-2-propano;1,3-Dibromo-isopropylalcohol;1,3-Dibromopropanol;1,3-Dibromopropylalcohol;2-Hydroxy-1,3-dibromopropane;alpha,gamma-Dibromohydrin;alpha-Dibromohydrin
• CAS NO: 96-21-9
• Molecular Formula: C₃H₆Br₂O
• Molecular Weight: 217.89
• EINECS: 202-489-8
• Product Categories: Organic Building Blocks;Oxygen Compounds;Polyols
• Mol File: 96-21-9.mol
• Article Data: 19

Chemical Properties

• Melting Point: 103-106 °C
• Boiling Point: 82-83 °C7 mm Hg(lit.)
• Flash Point: 116 °F
• Appearance: Clear colorless to light yellow or light brown/Liquid
• Density: 2.136 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00546mmHg at 25°C
• Refractive Index: n20/D 1.552(lit.)
• Storage Temp.: Refrigerator
• PKA: 12.46±0.20(Predicted)
• Water Solubility: soluble
• CAS DataBase Reference: 1,3-Dibromo-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dibromo-2-propanol(96-21-9)
• EPA Substance Registry System: 1,3-Dibromo-2-propanol(96-21-9)

Safety Data

• Hazard Codes: Xn,T
• Statements: 10-36/37/38-40-68-24/25-25
• Safety Statements: 16-26-36/37/39-45
• RIDADR: UN 1987 3/PG 3
• WGK Germany: 3
• RTECS: UB0200000
• HazardClass: 3.2
• PackingGroup: II
• Hazardous Substances Data: 96-21-9(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to light yellow liquid

Uses

1,3-Dibromo-2-propanol may be used in the following studies:To prepare the thioether ligand, used in the synthesis of palladium-phosphorus/sulfur nanoparticles.Preparation of 2-(alkoxy)propenyl bromide.Synthesis of 1,3-propanediamine derivatives connected to carbohydrates (sugar-pendant diamines).Chemical crosslinking of nine single substitution cysteine mutants of staphylococcal nuclease.Preparation of 1,3-dinitrooxy-2-propanol, via reaction with AgNO3 in MeCN at 80°C.

General Description

1,3-Dibromo-2-propanol is a dihalogenated alcohol. It is reported as bifunctional crosslinking reagent.

InChI:InChI=1/C3H6Br2O/c4-2-1-3(5)6/h3,6H,1-2H2

Upstream product

• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 106-95-6 allyl bromide 
• 56-81-5 glycerol 
• 67-56-1 methanol 
• 96-23-1 1,3-Dichloro-2-propanol 
• 124-38-9 carbon dioxide 
• 140428-44-0 1-bromo-3-phenoxy-propan-2-ol 
• 35995-55-2 (2-bromo-1-bromomethylethoxymethyl)benzene 
• 10035-10-6 hydrogen bromide 
• 83165-32-6 mono-(+)-2,3-Dibromopropylamine d-tartrate salt 

Downstream Products

• 13429-29-3 1,3-bispiperidin-1-ylpropan-2-ol 
• 6323-81-5 2,2'-dimethyl-1,1'-(2-hydroxy-propanediyl)-bis-pyridinium; dibromide 
• 99859-50-4 4-methyl-benzoic acid-(β,β'-dibromo-isopropyl ester) 
• 51483-40-0 1,3-dibromo-2-chloro-propane 
• 584-04-3 1,3-dimercapto-2-propanol 
• 816-39-7 1,3-dibromoroacetone 
• 107-18-6 allyl alcohol 
• 96-11-7 1,2,3-tribromopropane 
• 627-15-6 1,3-dibromopropene 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 107-02-8 acrolein 
• 99851-97-5 4-cyano-benzoic acid-(β,β'-dibromo-isopropyl ester) 
• 3492-47-5 1,3-bis(diethylamino)propan-2-ol 
• 58086-35-4 hexa-N-methyl-N,N'-(2-hydroxy-propanediyl)-di-ammonium; dibromide 

Relevant articles and documents

Bromotrimethylsilane as a selective reagent for the synthesis of bromohydrins

Bromotrimethylsilane (TMSBr) is a very efficient reagent in the solvent-free conversion of glycerol into bromohydrins, useful intermediates in the production of fine chemicals. As glycerol is a relevant by-product in biodiesel production, TMSBr has been also tested as a mediator in transesterification in acidic conditions, providing FAME from castor oil in good yields, along with bromohydrins from glycerol. Subsequently the glycerol conversion was optimized and depending on the reaction conditions, glycerol can be selectively converted into α-monobromohydrin (1-MBH) or α,γ-dibromohydrin (1,3-DBH) in very good yields. This journal is

Expeditious Syntheses to Pharmochemicals 1,3-Dihydroxyacetone, 1,3-Dichloro-, 1,3-Dibromo- And 1,3-Diiodoacetone from Glycerol 1,3-Dichlorohydrin Using Homogenous and Heterogenous Medium

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