96-11-7

Basic information

• Product Name: 1,2,3-Tribromopropane
• Synonyms: 1,2,3-tribromo-propan;Glyceryl tribromohydrin;glyceryltribromohydrin;Propane, 1,2,3-tribromo-;propane,1,2,3-tribromo-;s-Tribromopropane;sym-Tribromopropane;GLYCEROL TRIBROMOHYDRIN
• CAS NO: 96-11-7
• Molecular Formula: C₃H₅Br₃
• Molecular Weight: 280.78
• EINECS: 202-478-8
• Product Categories: Alkyl;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 96-11-7.mol
• Article Data: 14

Chemical Properties

• Melting Point: 16-17 °C(lit.)
• Boiling Point: 220 °C(lit.)
• Flash Point: 200 °F
• Appearance: /
• Density: 2.398 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.167mmHg at 25°C
• Refractive Index: n20/D 1.584(lit.)
• Storage Temp.: Store below +30°C.
• Solubility: H2O: insoluble
• Merck: 14,9614
• BRN: 1732082
• CAS DataBase Reference: 1,2,3-Tribromopropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-Tribromopropane(96-11-7)
• EPA Substance Registry System: 1,2,3-Tribromopropane(96-11-7)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-40-68
• Safety Statements: 26-27-36/37/39
• RIDADR: 2810
• WGK Germany: 3
• RTECS: TZ8300000
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: II
• Hazardous Substances Data: 96-11-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid. Soluble in alcohol and ether; insoluble in water.

General Description

1,2,3-Tribromopropane was mutagenic in strains TA1535 and TA100 of Salmonella typhimurium.

Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.

InChI:InChI=1/C3H5Br3/c4-1-3(6)2-5/h3H,1-2H2

Upstream product

• 556-56-9 allyl iodid 
• 78-75-1 1,2-Dibromopropane 
• 106-94-5 propyl bromide 
• 75-62-7 Bromotrichloromethane 
• 106-95-6 allyl bromide 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 96-21-9 1,3-dibromo-2-hydroxypropane 
• 7726-95-6 bromine 
• 71-43-2 benzene 
• 18854-66-5 tris(allyl)aluminum 
• 1253216-05-5 K[tetrakis(η1-allyl)aluminate] 
• 1253216-02-2 [Al(η1-C3H5)2(THF)2][BPh4] 
• 96-13-9 2,3-Dibromopropan-1-ol 
• 7697-37-2 nitric acid 

Downstream Products

• 66623-35-6 1,2-Bis(4-methylphenylsulfonyl)propane 
• 32133-84-9 1,2,3-tris-(toluene-4-sulfonyl)-propane 
• 555-44-2 glyceroltripalmitate 
• 555-43-1 glycerol tristearate 
• 63915-88-8 1-acetoxy-2-bromo-2-propene 
• 102-76-1 triacetylglycerol 
• 79629-42-8 2-bromoallyloxybenzene 
• 15515-75-0 1,2,3-tris(phenylsulfonyl)propane 
• 60-01-5 tributyrin 
• 614-33-5 glyceryl tribenzoate 
• 14295-64-8 glycerol tri(2-methylpropanoate) 
• 6915-08-8 octadec-9-enoic acid propane-1,2,3-triyl ester 
• 187737-37-7 propene 
• 76692-35-8 3-ethoxy-2-bromo-propene 

Relevant articles and documents

BROMINATED FLAME RETARDANTS AND POLYURETHANES CONTAINING THE SAME

The disclosure includes brominated alkenyl alcohols, their use as a flame retardant in polyurethane and polyurethane foams, and polyurethanes containing the brominated alkenyl alcohols. Compositions, methods, and processes are disclosed. The brominated alkenyl alcohols used as flame retardants in polyurethanes can be generally described by Formula (I), the scope of which is disclosed herein.

Ynamide Carbopalladation: A Flexible Route to Mono-, Bi- and Tricyclic Azacycles

Bromoenynamides represent precursors to a diversity of azacycles by a cascade sequence of carbopalladation followed by cross-coupling/electrocyclization, or reduction processes. Full details of our investigations into intramolecular ynamide carbopalladation are disclosed, which include the first examples of carbopalladation/cross-coupling reactions using potassium organotrifluoroborate salts; and an understanding of factors influencing the success of these processes, including ring size, and the nature of the coupling partner. Additional mechanistic observations are reported, such as the isolation of triene intermediates for electrocyclization. A variety of hetero-Diels-Alder reactions using the product heterocycles are also described, which provide insight into Diels-Alder regioselectivity.

Copper-catalyzed allylation of a,a-difluoro-substituted organozinc reagents

A method for the coupling of organozinc reagents, difluorocarbene, and allylic electrophiles is described. The reaction involves insertion of difluorocarbene into the carbon-zinc bond followed by copper-catalyzed allylic substitution.