2-Pyridinecarboxylic acid, 3-[(4-nitrobenzoyl)amino]-, methyl ester, 1-oxide

Base Information

• Chemical Name: 2-Pyridinecarboxylic acid, 3-[(4-nitrobenzoyl)amino]-, methyl ester, 1-oxide
• CAS No.: 400722-93-2
• Molecular Formula: C14H11N3O6
• Molecular Weight: 317.258
• Mol file: 400722-93-2.mol

Synonyms:

Chemical Property of 2-Pyridinecarboxylic acid, 3-[(4-nitrobenzoyl)amino]-, methyl ester, 1-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Pyridinecarboxylic acid, 3-[(4-nitrobenzoyl)amino]-, methyl ester, 1-oxide

There total 3 articles about 2-Pyridinecarboxylic acid, 3-[(4-nitrobenzoyl)amino]-, methyl ester, 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

methyl 3-p-nitrobenzoylaminopicolinate (400722-90-9) → methyl 3-nitrobenzoylaminopicolinate N-oxide (400722-93-2)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In acetonitrile; for 48h;

DOI:10.1021/jo000993j

Reference yield:

methyl 3-aminopicolinate (36052-27-4) → methyl 3-nitrobenzoylaminopicolinate N-oxide (400722-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / DMAP; pyridine / CHCl₃ / 4 h / Heating

2: 35 percent / m-CPBA / acetonitrile / 48 h

With pyridine; dmap; 3-chloro-benzenecarboperoxoic acid; In chloroform; acetonitrile;

DOI:10.1021/jo000993j

Reference yield:

4-nitro-benzoyl chloride (122-04-3) → methyl 3-nitrobenzoylaminopicolinate N-oxide (400722-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / DMAP; pyridine / CHCl₃ / 4 h / Heating

2: 35 percent / m-CPBA / acetonitrile / 48 h

With pyridine; dmap; 3-chloro-benzenecarboperoxoic acid; In chloroform; acetonitrile;

DOI:10.1021/jo000993j

upstream raw materials:

methyl 3-p-nitrobenzoylaminopicolinate

methyl 3-aminopicolinate

4-nitro-benzoyl chloride

Refernces