ETIOPORPHYRIN I

Base Information

• Chemical Name: ETIOPORPHYRIN I
• CAS No.: 448-71-5
• Molecular Formula: C32H38 N4
• Molecular Weight: 478.681
• Mol file: 448-71-5.mol

Synonyms:EtioporphyrinI (6CI,7CI); Porphine, 2,7,12,17-tetraethyl-3,8,13,18-tetramethyl- (8CI);2,7,12,17-Tetramethyl-3,8,13,18-tetraethylporphyrin; Etioporphyrin;Mesoetioporphyrin

Chemical Property of ETIOPORPHYRIN I

Chemical Property:

• Melting Point: >400 °C
• Boiling Point: 797.9°Cat760mmHg
• Flash Point: 341.3°C
• PSA: 56.30000
• Density: 1.101g/cm³
• LogP: 5.27440

Purity/Quality:

98%min ^*data from raw suppliers

EtioporphyrinI ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Etioporphyrin I is used as a phosporescent when complexed with certain metals.

Technology Process of ETIOPORPHYRIN I

There total 39 articles about ETIOPORPHYRIN I which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

5-(5-bromomethyl-4-ethyl-3-methyl-2H-pyrrol-2-ylidenemethyl)-2-bromo-4-ethyl-3-methyl-1H-pyrrole hydrobromide (4776-32-3) + 3,4'-diethyl-4,3'-dimethyl-5-bromo-5'-methyl-2,2'-dipyrrylmethene hydrobromide → ethioporphyrin I (448-71-5)

Guidance literature:

With hydrogen bromide; In formic acid; Heating;

DOI:10.1021/ja00297a024

Reference yield: 36.0%

5-Diethylaminomethyl-4-ethyl-3-methyl-1H-pyrrole-2-carboxylic acid (183164-05-8) → ethioporphyrin I (448-71-5)

Guidance literature:

With potassium hexacyanoferrate(III); In methanol; triethylamine; Heating;

DOI:10.1016/0040-4039(96)01632-2

Reference yield:

4-ethyl-5-methoxymethyl-3-methylpyrrole-2-carboxylic acid (94827-38-0) → 2,4,5,7-tetraethyl-1,3,6,8-tetramethylporphyrin (580-47-2) + ethioporphyrin I (448-71-5) + etioporphyrin II (448-70-4) + Etioporphyrin III (26608-34-4)

Guidance literature:

With K₁₀ montmorillonite; In dichloromethane; Yield given. Yields of byproduct given; in the dark; var. reag. HCl, AcOH, NaOAc, pyridine, H₂TPP, var.time and temp.;

upstream raw materials:

formic acid

(4-ethyl-5-bromomethyl-3-methyl-pyrrol-2-yliden)-(3-ethyl-5-bromo-4-methyl-pyrrol-2-yl)-methane; hydrobromide

5-bromo-3,4'-diethyl-4,3',5'-trimethyl-1H,2'H-2,2'-methanylylidene-bis-pyrrole

3-[5-(3-ethyl-5-carboxy-4-methyl-pyrrol-2-ylmethylene)-2,4-dimethyl-5H-pyrrol-3-yl]-propionic acid ; hydrobromide

Downstream raw materials:

cis-2,3-dihydroxy-etiochlorin

2,7,12,17-tetraethyl-3,8,13,18-tetramethyl-porphyrinogen-5,10,15,20-tetraone

1,2-dihydroxy-etiochlorin-I

3-ethyl-4-methyl-pyrrole-2,5-dione

Refernces

• 1、 Eaton, Sandra S.,Eaton, Gareth R.,Chang, C. K.. "Synthesis and Geometry Determination of Cofacial Diporphyrins. EPR Spectroscopy of Dicopper Diporphyrins in Frozen Solutions". . p. 3177 - 3184. Retrieved 1985.
• 2、 Markovac,MacDonald. "-". . p. 3364,3370. Retrieved 1965.
• 3、 Nguyen, Liem T.,Smith, Kevin M.. "Syntheses of type-I porphyrins via monopyrrole tetramerization". . p. 7177 - 7180. Retrieved 2007/10/03.
• 4、 Cheng, Lingjiang,Ma, Jinshi. "IMPROVED PREPARATIONS OF SYMMETRIC PORPHYRINS". . p. 224 - 228. Retrieved 2007/10/02.