(4-Hydroxyphenyl)diphenylmethanol

Base Information

• Chemical Name: (4-Hydroxyphenyl)diphenylmethanol
• CAS No.: 15658-11-4
• Molecular Formula: C19H16 O2
• Molecular Weight: 276.335
• Hs Code.: 2907299090
• European Community (EC) Number: 680-106-7
• NSC Number: 631514,97589
• DSSTox Substance ID: DTXSID70294656
• Wikidata: Q82034051
• Mol file: 15658-11-4.mol

Synonyms:15658-11-4;(4-Hydroxyphenyl)diphenylmethanol;4-(hydroxydiphenylmethyl)phenol;1,1-Diphenyl-4-hydroxyphenylmethanol;4-[hydroxy(diphenyl)methyl]phenol;4-(Hydroxy(diphenyl)methyl)phenol;NSC631514;4-Hydroxytrityl Alcohol;NSC97589;p-Hydroxytriphenylcarbinol;SCHEMBL8839028;DTXSID70294656;MFCD00973626;NSC-97589;NSC-631514;(R)-2-AMINO-4-BROMOBUTANOICACID;AS-64507;CS-0333994;FT-0637255;H1059;T71859;Benzenemethanol, 4-hydroxy-alpha,alpha-diphenyl-;A883566

Chemical Property of (4-Hydroxyphenyl)diphenylmethanol

Chemical Property:

• Vapor Pressure: 9.1E-10mmHg at 25°C
• Melting Point: 160.0 to 164.0 °C
• Boiling Point: 473.4°Cat760mmHg
• PKA: 10?+-.0.10(Predicted)
• Flash Point: 224.8°C
• PSA: 40.46000
• Density: 1.208g/cm³
• LogP: 3.67640
• Storage Temp.: 0-10°C
• Solubility.: soluble in Methanol
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 276.115029749
• Heavy Atom Count: 21
• Complexity: 290

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4-Hydroxyphenyl)diphenylmethanol >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)O)O

Technology Process of (4-Hydroxyphenyl)diphenylmethanol

There total 25 articles about (4-Hydroxyphenyl)diphenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

bromobenzene (108-86-1,52753-63-6) + 4-Hydroxybenzophenone (1137-42-4) → p-hydroxytrityl alcohol (15658-11-4)

Guidance literature:

bromobenzene; With iodine; magnesium; In tetrahydrofuran; for 6h; Inert atmosphere; Reflux;

4-Hydroxybenzophenone; In tetrahydrofuran; at 0 ℃; for 24h; Reflux;

DOI:10.1021/acscombsci.7b00068

Reference yield:

phenylmagnesium bromide (100-58-3) + 4-Hydroxybenzophenone (1137-42-4) → p-hydroxytrityl alcohol (15658-11-4)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 12h; Reflux;

Reference yield:

p-methoxytrityl alcohol (847-83-6) → p-hydroxytrityl alcohol (15658-11-4)

Guidance literature:

With aluminium trichloride; benzene;

upstream raw materials:

Ethyl 4-hydroxybenzoate

4-(diphenylmethylene)-2,5-cyclohexadienone

p-methoxytrityl alcohol

1-(p-bromophenyl)-1,1-diphenylcarbinol

Downstream raw materials:

α-Oxy-4-acetoxy-triphenylmethan

p-methoxytrityl alcohol

bisphenol TP

dicyclohexylmethane

Refernces

• 1、 -. "Compound containing diphenylmethane structure". Paragraph 0227; 0228; 0229; 0230. . Retrieved 2019/05/08.
• 2、 Andrews, Adrian F.,Mackie, Raymond K.,Walton, John C.. "The Reduction of Fluorine-containing Triarylmethanols by Formic Acid". . p. 96 - 102. Retrieved 2007/10/02.