Tolclofos-methyl

Base Information

• Chemical Name: Tolclofos-methyl
• CAS No.: 57018-04-9
• Deprecated CAS: 78617-09-1
• Molecular Formula: C9H11Cl2O3PS
• Molecular Weight: 301.13
• Hs Code.: 29201900
• European Community (EC) Number: 260-515-3
• UNII: G42OQL6F5B
• DSSTox Substance ID: DTXSID0034776
• Nikkaji Number: J1.904F
• Wikidata: Q1651656
• ChEMBL ID: CHEMBL2141416
• Mol file: 57018-04-9.mol

Synonyms:(O,O-dimethyl O-(2,6-dichloro-4-methylphenyl)phosphorothioate);tolclofos-methyl

Chemical Property of Tolclofos-methyl

Chemical Property:

• Vapor Pressure: 0.000191mmHg at 25°C
• Melting Point: 78-80 °C
• Refractive Index: 1.563
• Boiling Point: 338.5 °C at 760 mmHg
• Flash Point: 158.5 °C
• PSA: 69.59000
• Density: 1.401 g/cm³
• LogP: 4.84850
• Storage Temp.: 2-8°C
• Water Solubility.: 1.10 mg l-1 (25 °C)
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 299.9543578
• Heavy Atom Count: 16
• Complexity: 260

Purity/Quality:

99% ^*data from raw suppliers

Tolclofos-methyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,N
• Hazard Codes: Xi,N
• Statements: 43-50/53
• Safety Statements: 22-24/25-61-60-37-24

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)Cl)OP(=S)(OC)OC)Cl
• Uses: Agricultural fungicide. Tolclofos-methyl is a non-systemic organophosphorus fungicide with both protective and curative activities that control soil-borne diseases caused by Rhizoctonia solani, Corticium rolfsii, Tphula incamata and Typhula ishikariensis in/on potatoes, sugar beet, cotton and peanuts.

Technology Process of Tolclofos-methyl

There total 4 articles about Tolclofos-methyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dichloro-4-methylophenol (2432-12-4) + dimethyl chlorothiophosphate (2524-03-0) → tolclofos-methyl (57018-04-9,78617-09-1)

Guidance literature:

With copper(l) chloride; sodium hydroxide; In water; toluene; at 45 - 50 ℃; for 4.5h;

Reference yield:

2,6-dichloro-4-methylophenol (2432-12-4) + dimethyl chlorothiophosphate (2524-03-0) + sodium sulfate (7757-82-6) → tolclofos-methyl (57018-04-9,78617-09-1)

Guidance literature:

With potassium carbonate; In water; toluene;

Reference yield:

→ tolclofos-methyl (57018-04-9,78617-09-1)

Guidance literature:

upstream raw materials:

2,6-dichloro-4-methylophenol

dimethyl chlorothiophosphate

sodium sulfate

Downstream raw materials:

2,6-dichloro-4-methylphenyl methyl phosphorochloridothionate

Refernces

• 1、 -. "Pyrazolyl benzyl ether derivatives containing a fluoromethoxyimino group and use thereof as pesticides". . . Retrieved 2008/06/13.
• 2、 -. "Soil fungicidal phosphorothioate". . . Retrieved 2008/06/13.