ETHYL 4-HYDROXY-3,5-DIIODOBENZOATE

Base Information

• Chemical Name: ETHYL 4-HYDROXY-3,5-DIIODOBENZOATE
• CAS No.: 54073-94-8
• Molecular Formula: C9H8I2O3
• Molecular Weight: 417.97
• Hs Code.: 2918290000
• Mol file: 54073-94-8.mol

Synonyms:4-hydroxy-3,5-diiodo-benzoic acid ethyl ester;4-Hydroxy-3,5-dijod-benzoesaeure-aethylester;Ethyl-3,5-diiodo-4-hydroxybenzoate;3,5-Diiodoethyl-4-hydroxybenzoate;Benzoic acid, 4-hydroxy-3,5-diiodo-, ethyl ester;

Chemical Property of ETHYL 4-HYDROXY-3,5-DIIODOBENZOATE

Chemical Property:

• Melting Point: 119-122 °C
• Boiling Point: 342.6±42.0 °C(Predicted)
• PKA: 5.47±0.23(Predicted)
• PSA: 46.53000
• Density: 2.242±0.06 g/cm3(Predicted)
• LogP: 2.77810
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%Min ^*data from raw suppliers

Ethyl4-hydroxy-3,5-diiodobenzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 4-HYDROXY-3,5-DIIODOBENZOATE

There total 3 articles about ETHYL 4-HYDROXY-3,5-DIIODOBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Ethyl 4-hydroxybenzoate (120-47-8) → 4-hydroxy-3,5-diiodo-benzoic acid ethyl ester (54073-94-8)

Guidance literature:

With sodium hydrogencarbonate; N,N,N-trimethylbenzenemethanaminium dichloroiodate; In methanol; dichloromethane; for 7h; Ambient temperature;

DOI:10.1246/cl.1987.2109

Reference yield:

ethanol (64-17-5) + 3,5-diiodo-4-hydroxybenzoic acid (618-76-8) → 4-hydroxy-3,5-diiodo-benzoic acid ethyl ester (54073-94-8)

Guidance literature:

With hydrogenchloride;

Reference yield:

→ 4-hydroxy-3,5-diiodo-benzoic acid ethyl ester (54073-94-8)

Guidance literature:

Herstellung von 4-Hydroxy-3,5-di-<¹³¹I>jod-benzoesaeure-aethylester;

upstream raw materials:

Ethyl 4-hydroxybenzoate

ethanol

3,5-diiodo-4-hydroxybenzoic acid

Downstream raw materials:

C₃₀H₂₆N₂O₃

C₃₆H₃₇BN₂O₅

C₂₃H₂₀N₂O₃

ethyl 3,5-diiodo-4-methoxybenzoate

Refernces