5-METHOXYBENZOFURAZAN

Base Information

• Chemical Name: 5-METHOXYBENZOFURAZAN
• CAS No.: 4413-48-3
• Molecular Formula: C7H6 N2 O2
• Molecular Weight: 150.137
• Hs Code.: 2934999090
• Mol file: 4413-48-3.mol

Synonyms:Benzofurazan,5-methoxy- (7CI,8CI); 5-Methoxy-2,1,3-benzoxadiazole; 5-Methoxybenzofurazan;NSC 231418

Chemical Property of 5-METHOXYBENZOFURAZAN

Chemical Property:

• Vapor Pressure: 0.0685mmHg at 25°C
• Melting Point: 98-102 °C(lit.)
• Boiling Point: 237.6°Cat760mmHg
• Flash Point: 97.5°C
• PSA: 48.15000
• Density: 1.285g/cm³
• LogP: 1.23140

Purity/Quality:

98%min ^*data from raw suppliers

5-Methoxybenzofurazan ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn,Xi
• Statements: 22
• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 5-METHOXYBENZOFURAZAN

There total 2 articles about 5-METHOXYBENZOFURAZAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1-azido-4-methoxy-2-nitrobenzene (10336-13-7) → 5-methoxy-benzo[1,2,5]oxadiazole (4413-48-3) + 4-methoxy-2-nitroaniline (96-96-8)

Guidance literature:

1-azido-4-methoxy-2-nitrobenzene; With 9-phenyl-9-phosphafluorene; phenylsilane; In 1,4-dioxane; at 101 ℃; for 16h; Inert atmosphere;

With water; In 1,4-dioxane; at 20 ℃; Inert atmosphere;

DOI:10.1002/adsc.201100967

Reference yield:

4-methoxy-2-nitroaniline (96-96-8) → 5-methoxy-benzo[1,2,5]oxadiazole (4413-48-3) + 3-nitroanisole (555-03-3) + 4-methoxy-2-nitrophenol (1568-70-3) + 4-methoxy-[1,2]benzoquinone (69818-23-1) + 4-methoxycatechol (3934-97-2)

Guidance literature:

With ferrous(II) sulfate heptahydrate; dihydrogen peroxide; at 25 ℃; for 0.0166667h; pH=6.12; pH-value; Kinetics;

DOI:10.1039/c8ra00627j

Reference yield:

5-methoxy-benzo[1,2,5]oxadiazole (4413-48-3) + 1-phenylbutan-1,3-dione (93-91-4) → C17H14N2O4 (153757-42-7)

Guidance literature:

With silica gel; at 120 ℃; for 0.0833333h;

DOI:10.1371/journal.pone.0141076

upstream raw materials:

1-azido-4-methoxy-2-nitrobenzene

4-methoxy-2-nitroaniline

Downstream raw materials:

4-Brom-5-methoxy-benzofurazan

C₁₇H₁₄N₂O₄

Refernces

• 1、 Van Kalkeren, Henri A.,Bruins, Jorick J.,Rutjes, Floris P. J. T.,Van Delft, Floris L.. "Organophosphorus-catalysed Staudinger reduction". experimental part. p. 1417 - 1421. Retrieved 2012/07/03.