Benzenepropanoic acid, b-[(trimethylsilyl)amino]-, trimethylsilyl ester

Base Information

• Chemical Name: Benzenepropanoic acid, b-[(trimethylsilyl)amino]-, trimethylsilyl ester
• CAS No.: 58521-58-7
• Molecular Formula: C₁₅H₂₇NO₂Si₂
• Molecular Weight: 309.556
• Mol file: 58521-58-7.mol

Synonyms:

Chemical Property of Benzenepropanoic acid, b-[(trimethylsilyl)amino]-, trimethylsilyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenepropanoic acid, b-[(trimethylsilyl)amino]-, trimethylsilyl ester

There total 1 articles about Benzenepropanoic acid, b-[(trimethylsilyl)amino]-, trimethylsilyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + 3-Amino-3-phenylpropionic acid (3646-50-2) → (+/-)-trimethylsilyl β-(N-trimethylsilylamino)-β-phenylpropionate (58521-58-7)

Guidance literature:

With triethylamine; In benzene;

Reference yield:

(+/-)-trimethylsilyl β-(N-trimethylsilylamino)-β-phenylpropionate (58521-58-7) → 4-phenylazetidin-2-one (5661-55-2)

Guidance literature:

With ethylmagnesium bromide; In diethyl ether; at 0 - 20 ℃; for 14h;

DOI:10.1007/s00706-002-0485-8

upstream raw materials:

chloro-trimethyl-silane

3-Amino-3-phenylpropionic acid

Downstream raw materials:

4-phenylazetidin-2-one

Refernces