2-phenoxycyclopropanecarboxylic acid

Base Information

• Chemical Name: 2-phenoxycyclopropanecarboxylic acid
• CAS No.: 7252-94-0
• Molecular Formula: C10H10 O3
• Molecular Weight: 178.1846
• Mol file: 7252-94-0.mol

Synonyms:NSC 19800

Chemical Property of 2-phenoxycyclopropanecarboxylic acid

Chemical Property:

• Vapor Pressure: 4.54E-05mmHg at 25°C
• Boiling Point: 336°Cat760mmHg
• Flash Point: 137.5°C
• Density: 1.32g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-phenoxycyclopropanecarboxylic acid

There total 16 articles about 2-phenoxycyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Phenoxy-cyclopropan-2-carbonsaeure-aethylester (5362-38-9) → 2-phenoxycyclopropane carboxylic acid (7252-94-0)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 12h; Yield given; Heating;

DOI:10.1021/ja00247a033

Reference yield:

vinyl phenyl ether (766-94-9) → 2-phenoxycyclopropane carboxylic acid (7252-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent / Cu powder / xylene / 1 h / Heating

2: NaOH / ethanol; H₂O / 12 h / Heating

With sodium hydroxide; copper; In ethanol; water; xylene;

DOI:10.1021/ja00247a033

Reference yield:

vinyl phenyl ether (766-94-9) → (+/-)-cis-2-phenoxy-cyclopropanecarboxylic acid (2120-93-6,2120-94-7,7252-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Cu / xylene / Heating

2: aq. NaOH / ethanol / Heating

With sodium hydroxide; copper; In ethanol; xylene;

DOI:10.1021/jm00328a005

upstream raw materials:

1-Phenoxy-cyclopropan-2-carbonsaeure-aethylester

vinyl phenyl ether

diazoacetic acid ethyl ester

(+/-)-cis-2-phenoxy-cyclopropanecarbonyl chloride

Downstream raw materials:

Methyl-<2-phenoxy-cyclopropyl>-keton

succinic semialdehyde 2,4-dinitrophenylhydrazone

(+/-)-trans-2-phenoxy-cyclopropanecarboxylic acid amide

(+/-)-trans-2-phenoxy-cyclopropanecarbonyl chloride

Refernces

• 1、 Finkelstein,Chiang,Lee. "Synthesis of cis- and trans-2-phenoxycyclopropylamines and related compounds.". . p. 432 - 439. Retrieved 2007/10/06.