N-Fluoren-2-ylbenzohydroxamic acid, acetate

Base Information

• Chemical Name: N-Fluoren-2-ylbenzohydroxamic acid, acetate
• CAS No.: 29968-75-0
• Molecular Formula: C22H17 N O3
• Molecular Weight: 343.40
• DSSTox Substance ID: DTXSID50952388
• Nikkaji Number: J3.171B
• Wikidata: Q82930967
• Mol file: 29968-75-0.mol

Synonyms:N-Fluoren-2-ylbenzohydroxamic acid, acetate;29968-75-0;[benzoyl(9H-fluoren-2-yl)amino] acetate;N-Acetoxy-2-fluorenylbenzamide;N-Acetoxy-N-(9H-fluoren-2-yl)benzamide;BENZOHYDROXAMIC ACID, N-FLUOREN-2-YL-, ACETATE;DTXSID50952388;LS-35436;N-Acetoxy-N-(9H-fluorene-2-yl)benzamide;N-(Acetyloxy)-N-(9H-fluoren-2-yl)benzamide

Chemical Property of N-Fluoren-2-ylbenzohydroxamic acid, acetate

Chemical Property:

• Vapor Pressure: 5.62E-11mmHg at 25°C
• Refractive Index: 1.5614 (estimate)
• Boiling Point: 521.6°Cat760mmHg
• Flash Point: 269.2°C
• PSA: 46.61000
• Density: 1.292g/cm³
• LogP: 4.38270
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 343.12084340
• Heavy Atom Count: 26
• Complexity: 528

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)ON(C1=CC2=C(C=C1)C3=CC=CC=C3C2)C(=O)C4=CC=CC=C4

Technology Process of N-Fluoren-2-ylbenzohydroxamic acid, acetate

There total 3 articles about N-Fluoren-2-ylbenzohydroxamic acid, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

lead(IV) tetraacetate (546-67-8) + α-phenyl-N-(2-aminofluorenyl)nitrone (411240-48-7) → N-acetoxy-N-benzoyl-2-fluorenylamine (29968-75-0)

Guidance literature:

In benzene; at 0 ℃; for 0.166667h;

DOI:10.1055/s-2001-18718

Reference yield:

2-nitro-9H-fluorene (607-57-8) → N-acetoxy-N-benzoyl-2-fluorenylamine (29968-75-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 91 percent / Zn; aq. NH₄Cl; histidine / 0.75 h / 20 - 30 °C / pH 7.4 - 7.5

2: 95 percent / ethanol / 0 - 15 °C

3: 87 percent / benzene / 0.17 h / 0 °C

With ammonium chloride; D,L-histidine; zinc; In ethanol; benzene;

DOI:10.1055/s-2001-18718

Reference yield:

N-(9H-fluoren-2-yl)hydroxylamine (53-94-1) → N-acetoxy-N-benzoyl-2-fluorenylamine (29968-75-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / ethanol / 0 - 15 °C

2: 87 percent / benzene / 0.17 h / 0 °C

In ethanol; benzene;

DOI:10.1055/s-2001-18718

upstream raw materials:

lead(IV) tetraacetate

α-phenyl-N-(2-aminofluorenyl)nitrone

2-nitro-9H-fluorene

N-(9H-fluoren-2-yl)hydroxylamine

Downstream raw materials:

2-fluoren

N-(benzoyl)-N-(deoxyguanosin-8-yl)-2-aminofluorene

Refernces