2-Nitrofluorene

Base Information

• Chemical Name: 2-Nitrofluorene
• CAS No.: 607-57-8
• Molecular Formula: C13H9NO2
• Molecular Weight: 211.22
• Hs Code.: 29042000
• European Community (EC) Number: 210-138-5
• NSC Number: 5182
• UNII: 191LL4U4GZ
• DSSTox Substance ID: DTXSID2020971
• Nikkaji Number: J2.988B
• Wikipedia: 2-Nitrofluorene
• Wikidata: Q4596909
• Metabolomics Workbench ID: 52850
• ChEMBL ID: CHEMBL351487
• Mol file: 607-57-8.mol

Synonyms:2-nitrofluorene

Chemical Property of 2-Nitrofluorene

Chemical Property:

• Appearance/Colour: cream powder
• Vapor Pressure: 1.77E-05mmHg at 25°C
• Melting Point: 156-158 °C(lit.)
• Refractive Index: 1.677
• Boiling Point: 374.7 °C at 760 mmHg
• Flash Point: 185.2 °C
• PSA: 45.82000
• Density: 1.318 g/cm³
• LogP: 3.68920
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility.: Insoluble
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 211.063328530
• Heavy Atom Count: 16
• Complexity: 286

Purity/Quality:

99% ^*data from raw suppliers

2-Nitrofluorene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,N
• Statements: 40-51/53-68
• Safety Statements: 36/37-61

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Polycyclic Aromatic Hydrocarbons
• Canonical SMILES: C1C2=CC=CC=C2C3=C1C=C(C=C3)[N+](=O)[O-]
• Uses: 2-Nitrofluorene is a genotoxic compound and also a biomaker that affects the DNA of living organisms. An environmental pollutant.

Technology Process of 2-Nitrofluorene

There total 23 articles about 2-Nitrofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-nitro-9H-fluoren-9-one (3096-52-4) → 2-nitro-9H-fluorene (607-57-8)

Guidance literature:

With hydrazine hydrate; In various solvent(s); at 158 ℃;

DOI:10.1246/bcsj.69.3633

Reference yield: 92.0%

9H-fluorene (86-73-7) → 2-nitro-9H-fluorene (607-57-8)

Guidance literature:

With nitric acid; acetic acid; at 60 ℃; for 0.166667h;

DOI:10.3762/bjoc.12.163

Reference yield: 86.0%

9H-fluorene (86-73-7) → 2-nitro-9H-fluorene (607-57-8) + 4-nitrofluorene (24237-68-1)

Guidance literature:

With sulfuric acid; nitric acid; silica gel; In dichloromethane; at 25 ℃; for 24h;

DOI:10.1080/00397919908085892

upstream raw materials:

9H-fluorene

2-Hydroxymethyl-4-nitrobiphenyl

2-aminofluorene

2-nitro-9H-fluoren-9-one

Downstream raw materials:

9-bromo-2-nitro-fluorene

9-cinnamylidene-2-nitro-fluorene

N,N-dimethyl-4-(2-nitro-fluoren-9-ylidenemethyl)-aniline

2,2'-azofluorene

Refernces

• 1、 Hosseinzadeh, Rahman,Rahimi, Hannaneh,Tajbakhsh, Mahmood. "A new and efficient pyridine-2,6-dicarboxamide-based fluorescent and colorimetric chemosensor for sensitive and selective recognition of Pb2+ and Cu2+". . . Retrieved 2020/12/02.
• 2、 Tajbakhsh, Mahmood,Chalmardi, Gholam Babaei,Bekhradnia, Ahmadreza,Hosseinzadeh, Rahman,Hasani, Nahid,Amiri, Mohammadreza Azizi. "A new fluorene-based Schiff-base as fluorescent chemosensor for selective detection of Cr3?+ and Al3?+". . p. 22 - 31. Retrieved 2017/08/08.