Propanamide, N-9H-fluoren-2-yl-N-hydroxy-

Base Information

• Chemical Name: Propanamide, N-9H-fluoren-2-yl-N-hydroxy-
• CAS No.: 52663-84-0
• Molecular Formula: C₁₆H₁₅NO₂
• Molecular Weight: 253.301
• DSSTox Substance ID: DTXSID70967090
• Nikkaji Number: J71.066K
• Wikidata: Q82949599
• ChEMBL ID: CHEMBL168800
• Mol file: 52663-84-0.mol

Synonyms:N-(2-Fluorenyl)propionohydroxamic acid;52663-84-0;Propanamide, N-9H-fluoren-2-yl-N-hydroxy-;N-Hydroxy-N-2-propionylamino fluorene;n-(9h-fluoren-2-yl)-n-hydroxypropanamide;N-Propionyl-N-2-fluorenylhydroxylamine;N-Propionyl-N-hydroxy-2-aminofluorene;Propionohydroxamic acid, N-(2-fluorenyl)-;CHEMBL168800;DTXSID70967090;N-hydroxy-N-2-fluorenylpropion-amide

Chemical Property of Propanamide, N-9H-fluoren-2-yl-N-hydroxy-

Chemical Property:

• Vapor Pressure: 2.36E-09mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 462.5°Cat760mmHg
• Flash Point: 233.5°C
• PSA: 40.54000
• Density: 1.282g/cm³
• LogP: 3.39000
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 253.110278721
• Heavy Atom Count: 19
• Complexity: 344

Purity/Quality:

99% ^*data from raw suppliers

N-(2-FLUORENYL)PROPIONOHYDROXAMIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(=O)N(C1=CC2=C(C=C1)C3=CC=CC=C3C2)O

Technology Process of Propanamide, N-9H-fluoren-2-yl-N-hydroxy-

There total 2 articles about Propanamide, N-9H-fluoren-2-yl-N-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-9H-fluorene (607-57-8) → N-hydroxy-N-propionyl-2-aminofluorene (52663-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₄Cl, Zn / dimethylformamide; ethanol; H₂O / 3 h / Ambient temperature

2: NaHCO₃ / diethyl ether / Ambient temperature

With sodium hydrogencarbonate; ammonium chloride; zinc; In diethyl ether; ethanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jm00349a015

Reference yield:

N-(9H-fluoren-2-yl)hydroxylamine (53-94-1) + propionyl chloride (79-03-8) → N-hydroxy-N-propionyl-2-aminofluorene (52663-84-0)

Guidance literature:

With sodium hydrogencarbonate; In diethyl ether; Yield given; Ambient temperature;

DOI:10.1021/jm00349a015

upstream raw materials:

N-(9H-fluoren-2-yl)hydroxylamine

propionyl chloride

2-nitro-9H-fluorene

Refernces