1,2-Dichloro-2-fluoropropane

Base Information

• Chemical Name: 1,2-Dichloro-2-fluoropropane
• CAS No.: 420-97-3
• Molecular Formula: C3H5 Cl2 F
• Molecular Weight: 130.977
• Hs Code.: 2903791090
• European Community (EC) Number: 206-999-1
• DSSTox Substance ID: DTXSID70870530
• Nikkaji Number: J79.615H
• Mol file: 420-97-3.mol

Synonyms:1,2-Dichloro-2-fluoropropane;420-97-3;HCFC-261;1,2-dichloro-2-fluoro-propane;Propane, 1,2-dichloro-2-fluoro-;EINECS 206-999-1;HCFC-261ba;C3H5Cl2F;SCHEMBL1992061;1,2-Dichloro-2-fluoro propane;DTXSID70870530;MFCD00042126;AKOS006229026;7-(a-Bromoacetamido)cephalosporanicacid;1,2-bis(chloranyl)-2-fluoranyl-propane;FT-0606376;A825759;A826772

Chemical Property of 1,2-Dichloro-2-fluoropropane

Chemical Property:

• Vapor Pressure: 68.2mmHg at 25°C
• Melting Point: -92,5°C
• Refractive Index: 1.2618
• Boiling Point: 88-89°C
• Flash Point: 3.6°C
• PSA: 0.00000
• Density: 1.231g/cm³
• LogP: 2.14970
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 129.9752337
• Heavy Atom Count: 6
• Complexity: 48.1

Purity/Quality:

98%min ^*data from raw suppliers

1,2-Dichloro-2-fluoropropane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 10
• Safety Statements: 16

MSDS Files:

Useful:

• Canonical SMILES: CC(CCl)(F)Cl

Technology Process of 1,2-Dichloro-2-fluoropropane

There total 10 articles about 1,2-Dichloro-2-fluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-Dichloroprop-1-ene (78-88-6) → 1-chloro-2,2-difluoropropane (420-99-5) + 1,2,2-trichloropropane (3175-23-3) + 1,2-dichloro-2-fluoro-propane (420-97-3)

Guidance literature:

With hydrogen fluoride; at 50 - 60 ℃; for 12h; Further byproducts given;

DOI:10.1021/jo01014a050

Reference yield:

2,2-difluoropropane (420-45-1) → 1-chloro-2,2-difluoropropane (420-99-5) + 1,2,2-trichloropropane (3175-23-3) + 1,2-dichloro-2-fluoro-propane (420-97-3)

Guidance literature:

With hydrogenchloride; hydrogen fluoride; chlorine; at 100 ℃; for 5h; Yield given. Yields of byproduct given; stainless-steel autoclave;

Reference yield:

2,3-Dichloroprop-1-ene (78-88-6) → 1-chloro-2,2-difluoropropane (420-99-5) + 1,2-dichloro-2-fluoro-propane (420-97-3)

Guidance literature:

With hydrogen fluoride; diphenylamine; at 122 ℃;

DOI:10.1021/ie50538a058

upstream raw materials:

2,3-Dichloroprop-1-ene

1,2-dichloro-propene

2-fluoropropene

2,2-difluoropropane

Downstream raw materials:

1,1,1,2,3,3,3-heptachloro-2-fluoro-propane

1,1,1,2,3,3-hexachloro-2-fluoro-propane

1,1,1,2-tetrachloro-2-fluoro-propane

1,1,1,2,3-pentachloro-2-fluoro-propane

Refernces

• 1、 -. "Fluorination process using hydrogen fluoride-containing fluorinating agents". . . Retrieved 2008/06/13.