2,2-Difluoropropane

Base Information

• Chemical Name: 2,2-Difluoropropane
• CAS No.: 420-45-1
• Molecular Formula: C3H6F2
• Molecular Weight: 80.0774
• Hs Code.: 2903399090
• DSSTox Substance ID: DTXSID60870529
• Nikkaji Number: J110.643K
• Wikidata: Q81978223
• Mol file: 420-45-1.mol

Synonyms:2,2-Difluoropropane;420-45-1;Propane, 2,2-difluoro-;Dimethyldifluoromethane;R 272ca;C3H6F2;(CH3)2CF2;DTXSID60870529;MFCD00039267;AKOS004904115;FT-0609239;FT-0628739

Chemical Property of 2,2-Difluoropropane

Chemical Property:

• Vapor Pressure: 2010mmHg at 25°C
• Melting Point: -104.8°C
• Refractive Index: 1.292
• Boiling Point: -1 °C at 760 mmHg
• PSA: 0.00000
• Density: 0.899 g/cm³
• LogP: 1.66150
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 80.04375652
• Heavy Atom Count: 5
• Complexity: 27.9

Purity/Quality:

99% ^*data from raw suppliers

2,2-Difluoropropane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-33

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(F)F

Technology Process of 2,2-Difluoropropane

There total 8 articles about 2,2-Difluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) → carbon tetrafluoride (75-73-0) + freon-218 (76-19-7) + propane (74-98-6) + 2-propylfluoride (420-26-8) + 2,2-difluoropropane (420-45-1) + Hexafluoroethane (76-16-4)

Guidance literature:

With hydrogen fluoride; sodium fluoride; at 0 ℃; for 18h; Product distribution; electrochemical fluorination; anode and cathode: nickel foam; anode potential versus nickel reference electrod 4.0 V; effect of anode potential; effect of dilution; effect of propene flow rate; effect of the anode conditioning;

DOI:10.1016/S0022-1139(00)80509-6

Reference yield:

propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) → carbon tetrafluoride (75-73-0) + freon-218 (76-19-7) + 2,2-difluoropropane (420-45-1) + Hexafluoroethane (76-16-4)

Guidance literature:

With hydrogen fluoride; at -7 ℃; for 18h; Yield given. Yields of byproduct given; elecrochemical fluorination; anode and cathode: nickel foam; anode pot. versus reference electrode 4.80 V;

DOI:10.1016/S0022-1139(00)80509-6

Reference yield:

tert-butylfluoride (353-61-7) → 2,2-difluoropropane (420-45-1) + 2-fluoropropene (1184-60-7)

Guidance literature:

Mechanism; structures of the various alkyl fluoride ions derived with 70 eV electron bombardment;

DOI:10.1021/ja00290a007

upstream raw materials:

2,2-dichloropropane

propene

1,2-propanediene

tert-butylfluoride

Downstream raw materials:

1,1,1,3,3-pentachloro-2,2-difluoropropane

2-fluoropropene

1,1-dichloro-2,2-difluoropropane

1,1,1-Trichlor-2,2-difluor-propan

Refernces

• 1、 Arimura, Takashi,Kurosawa, Shigeru,Sekiya, Akira. "A New Preparative Method for 1-Chloro-2,2,3-trifluoropropane (HCFC-253ca)". . p. 35 - 36. Retrieved 2007/10/02.
• 2、 Redman, Eric W.,Johri, Kamalesh K.,Morton, Thomas Hellman. "Structures of Organic Cations in the Gas Phase. Neutral Products from Fluoride Abstraction Examined by NMR". . p. 780 - 784. Retrieved 2007/10/02.