2-NP-AHD

Base Information

• Chemical Name: 2-NP-AHD
• CAS No.: 623145-57-3
• Molecular Formula: C₁₀H₈N₄O₄
• Molecular Weight: 248.198
• Mol file: 623145-57-3.mol

Synonyms:

Chemical Property of 2-NP-AHD

Chemical Property:

• Melting Point: 220-221°C
• PKA: 7.76±0.10(Predicted)
• PSA: 107.59000
• Density: 1.58±0.1 g/cm3(Predicted)
• LogP: 1.27040
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly)

Purity/Quality:

NLT 98% ^*data from raw suppliers

NP-AHD ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A derivative of the metabolite of nitrofuran antibiotics, 1-aminohydantoin (AH A derivative of the metabolite of nitrofuran antibiotics, 1-aminohydantoin (AH) (A611090).Environmental contaminants; Food contaminants; Heat processing contaminants

Technology Process of 2-NP-AHD

There total 2 articles about 2-NP-AHD which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-aminohydantoin (6301-02-6) + 2-nitro-benzaldehyde (552-89-6) → 1-(2-nitrobenzylideneamino)hydantoin (623145-57-3)

Guidance literature:

In methanol; N,N-dimethyl-formamide; at 65 ℃; Reflux;

DOI:10.1016/j.jpba.2017.06.068

Reference yield:

1-aminohydantoin hydrochloride (2827-56-7) + 2-nitro-benzaldehyde (552-89-6) → 1-(2-nitrobenzylideneamino)hydantoin (623145-57-3)

Guidance literature:

With hydrogenchloride; In methanol; water; at 37 ℃;

DOI:10.1021/acs.jafc.7b01050

upstream raw materials:

1-aminohydantoin

2-nitro-benzaldehyde

1-aminohydantoin hydrochloride

Refernces

• 1、 Wu, Siyang,Yang, Binghu,Yu, Huiqing,Li, Yingfei. "A rapid derivatization method for analyzing nitrofuran metabolites in fish using ultra-performance liquid chromatography-tandem mass spectrometry". . . Retrieved 2019/11/26.