P-TOLYL VINYL SULPHONE

Base Information

• Chemical Name: P-TOLYL VINYL SULPHONE
• CAS No.: 5535-52-4
• Molecular Formula: C9H10O2S
• Molecular Weight: 182.243
• Hs Code.: 2904100000
• Mol file: 5535-52-4.mol

Synonyms:1-Methyl-4-(vinylsulfonyl)benzene;1-(Ethenylsulfonyl)-4-methylbenzene;4-Methylphenyl vinyl sulfone;p-Tolyl vinyl sulfone;p-Tosylethylene;Sulfone, p-tolyl vinyl;

Chemical Property of P-TOLYL VINYL SULPHONE

Chemical Property:

• Melting Point: 62-64°C
• Refractive Index: 1.631
• Boiling Point: 324.1 °C at 760 mmHg
• Flash Point: 181.5 °C
• PSA: 42.52000
• Density: 1.145 g/cm³
• LogP: 2.99300

Purity/Quality:

99%, ^*data from raw suppliers

PARA-TOLYL VINYL SULPHONE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of P-TOLYL VINYL SULPHONE

There total 26 articles about P-TOLYL VINYL SULPHONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-tosylethyl 3-phenylpropanoate (112471-52-0) → tolyl vinyl sulfone (5535-52-4) + 3-Phenylpropionic acid (501-52-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1246/cl.1987.1595

Reference yield: 92.0%

2-tosylethyl 3-phenyl-2-propenoate (112471-53-1) → tolyl vinyl sulfone (5535-52-4) + Cinnamic acid (621-82-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1246/cl.1987.1595

Reference yield: 81.0%

ethene (74-85-1) + sodium 4-methylbenzenesulfinate (824-79-3) → tolyl vinyl sulfone (5535-52-4)

Guidance literature:

With iodine; In water; ethyl acetate; for 5h; Ambient temperature;

DOI:10.1246/bcsj.67.3088

upstream raw materials:

2-(p-tolylsulfonyl)ethanol

p-tolyl vinyl sulfide

2-chloroethyl-p-toluenesulfonate

triethylamine

Downstream raw materials:

3-[(4-methylbenzene)sulfonyl]propanenitrile

1-ethanesulfonyl-2-(toluene-4-sulfonyl)-ethane

1-(4-chloro-2-methyl-phenylsulfanyl)-2-(toluene-4-sulfonyl)-ethane

ethyl-[2]naphthyl-[2-(toluene-4-sulfonyl)-ethyl]-amine

Refernces

• 1、 Strieth-Kalthoff,Henkel, Christian,Teders, Michael,Kahnt, Axel,Knolle, Wolfgang,Gómez-Suárez, Adrián,Dirian, Konstantin,Alex, Wiebke,Bergander,Daniliuc, Constantin G.,Abel,Guldi, Dirk M.,Glorius. "Discovery of Unforeseen Energy-Transfer-Based Transformations Using a Combined Screening Approach". supporting information. p. 2183 - 2194. Retrieved 2019/08/08.
• 2、 Dong, Jun,Xu, Jiaxi. "Safe and Metal-Free Synthesis of 1-Alkenyl Aryl Sulfides and Their Sulfones from Thiiranes and Diaryliodonium Salts". . p. 2407 - 2415. Retrieved 2018/04/16.