Sulfone, 2-chloroethyl p-tolyl

Base Information

• Chemical Name: Sulfone, 2-chloroethyl p-tolyl
• CAS No.: 22381-53-9
• Molecular Formula: C9H11 Cl O2 S
• Molecular Weight: 218.704
• Hs Code.: 2904909090
• NSC Number: 9012
• DSSTox Substance ID: DTXSID00276682
• Nikkaji Number: J145.075A
• Wikidata: Q82007328
• Mol file: 22381-53-9.mol

Synonyms:22381-53-9;Sulfone, 2-chloroethyl p-tolyl;2-CHLOROETHYL P-TOLYL SULFONE;1-((2-Chloroethyl)sulfonyl)-4-methylbenzene;1-(2-chloroethylsulfonyl)-4-methylbenzene;Benzene,1-[(2-chloroethyl)sulfonyl]-4-methyl-;Benzene, 1-[(2-chloroethyl)sulfonyl]-4-methyl-;p-Toluene 2-chloroethyl sulphone;1-(2-chloroethanesulfonyl)-4-methylbenzene;SCHEMBL1149166;DTXSID00276682;NSC9012;(2-Chloroethyl)(p-tolyl) sulfone;NSC 9012;NSC-9012;MFCD00051607;AKOS009157572;CS-0336354;FT-0611947;1-(2-chloro-ethanesulfonyl)-4-methyl-benzene;1-(2-chloro-ethanesulfonyl)-4-methyl -benzene

Chemical Property of Sulfone, 2-chloroethyl p-tolyl

Chemical Property:

• Vapor Pressure: 2.97E-05mmHg at 25°C
• Melting Point: 77 °C
• Boiling Point: 367°Cat760mmHg
• Flash Point: 175.8°C
• PSA: 42.52000
• Density: 1.247g/cm³
• LogP: 3.08830
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 218.0168285
• Heavy Atom Count: 13
• Complexity: 235

Purity/Quality:

99% ^*data from raw suppliers

2-CHLOROETHYL P-TOLYL SULFONE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)CCCl

Technology Process of Sulfone, 2-chloroethyl p-tolyl

There total 9 articles about Sulfone, 2-chloroethyl p-tolyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(2-chloro-ethyl)-p-tolyl sulfide (20761-71-1) → 2-chloroethyl-p-toluenesulfonate (22381-53-9)

Guidance literature:

With dihydrogen peroxide; In acetic acid;

Reference yield: 85.0%

sodium 4-methylbenzenesulfinate (824-79-3) + 1-Bromo-2-chloroethane (107-04-0) → 2-chloroethyl-p-toluenesulfonate (22381-53-9)

Guidance literature:

In N,N-dimethyl-formamide; for 24h; Ambient temperature;

Reference yield:

ethene (74-85-1) + p-toluenesulfonyl chloride (98-59-9) → 2-chloroethyl-p-toluenesulfonate (22381-53-9)

Guidance literature:

With aluminium trichloride;

upstream raw materials:

(2-chloro-ethyl)-p-tolyl sulfide

2-(p-tolylsulfonyl)ethanol

2-(p-tolylthio)-ethanol

para-thiocresol

Downstream raw materials:

tolyl vinyl sulfone

7-(2-Chlor-ethyl)-7H-benzophenthiazin

7-(2-Chlor-aethyl)-7H-dibenzophenthiazin

14-(2-Chlor-aethyl)-14H-dibenzophenthiazin

Refernces

• 1、 Alonso, Diego A.,Arques, Antonio,Najera, Carmen,Sansano, Jose M.. "A Very Simple and Convenient Synthesis of Tosylethylene and (E)-1,2-Ditosylethylene". . p. 449 - 452. Retrieved 2007/10/03.