2,6-Dimethyl-4-Hydroxypyridine

Base Information Edit

Chemical Name:2,6-Dimethyl-4-Hydroxypyridine
CAS No.:13603-44-6
Molecular Formula:C7H9NO
Molecular Weight:123.155
Hs Code.:29333990
European Community (EC) Number:237-089-2
NSC Number:111932
UNII:92JKJ9S198
DSSTox Substance ID:DTXSID70929234
Nikkaji Number:J277.954D,J952.958F
Wikidata:Q27271513
ChEMBL ID:CHEMBL1429618
Mol file:13603-44-6.mol

Synonyms:2,6-Dimethyl-4-Hydroxypyridine;13603-44-6;2,6-Dimethylpyridin-4-ol;2,6-dimethylpyridin-4(1H)-one;7516-31-6;4-hydroxy-2,6-dimethylpyridine;2,6-dimethyl-1H-pyridin-4-one;2,6-Dimethyl-4-pyridinol;4-Pyridinol, 2,6-dimethyl-;2,6-Dimethyl-4-hydroxy pyridine;2,6-Dimethyl-4(1H)-pyridone;2,6-dimethyl-1,4-dihydropyridin-4-one;UNII-92JKJ9S198;MLS000056906;2,6-dimethyl-4(1H)-pyridinone;4(1H)-Pyridinone,2,6-dimethyl;92JKJ9S198;EINECS 237-089-2;4(1H)-Pyridinone, 2,6-dimethyl-;MFCD00956021;NSC-111932;SMR000065470;NSC111932;2,6-Dimethylpyridine-4-ol;2,6-Dimethyl-pyridin-4-ol;cid_83609;SCHEMBL275728;2,6-dimethyl-4(1h)pyridone;2,6-Dimethyl-4-pyridinol #;CHEMBL1429618;BDBM38374;4-HYDROXY-2,6-LUTIDINE;DTXSID70929234;2,6-dimethyl-4-(1H)-pyridone;HMS2492I09;2,6-Dimethylpyridine-4(1H)-one;BCP26600;MFCD00100799;STK051921;AKOS001021914;AKOS006229750;AB07775;AC-6757;CS-W013538;FG-0432;NSC 111932;SB52678;SY019779;A2911;AM20070003;D3638;FT-0636927;EN300-92391;2,6-dimethylpyridin-4-ol;W-205479;Q27271513;Z56754506

Suppliers and Price of 2,6-Dimethyl-4-Hydroxypyridine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-Dimethyl-4-hydroxypyridine
25g
$ 300.00

TRC
2,6-Dimethyl-4-hydroxypyridine
2.5g
$ 110.00

TCI Chemical
2,6-Dimethyl-4-hydroxypyridine >98.0%(GC)
5g
$ 183.00

TCI Chemical
2,6-Dimethyl-4-hydroxypyridine >98.0%(GC)
1g
$ 38.00

SynQuest Laboratories
2,6-Dimethyl-4-hydroxypyridine 98%
25 g
$ 85.00

SynQuest Laboratories
2,6-Dimethyl-4-hydroxypyridine 98%
5 g
$ 18.00

Matrix Scientific
2,6-Dimethyl-4-hydroxypyridine 98%
5g
$ 16.00

Matrix Scientific
2,6-Dimethyl-4-hydroxypyridine 98%
25g
$ 77.00

Matrix Scientific
2,6-Dimethyl-4-hydroxypyridine 98%
100g
$ 224.00

Labseeker
2,6-DIMETHYL-4-HYDROXYPYRIDINE 98
10g
$ 333.00

Total 87 raw suppliers

Chemical Property of 2,6-Dimethyl-4-Hydroxypyridine Edit

Chemical Property:

Appearance/Colour:yellow to brown cryst
Vapor Pressure:0.251mmHg at 25°C
Melting Point:230-232 °C
Refractive Index:1,501-1,503
Boiling Point:205.4 °C at 760 mm
PKA:5.49±0.23(Predicted)
Flash Point:93.1 °C
PSA：33.12000
Density:1.013 g/cm³
LogP:1.40400
Storage Temp.:Room temperature.
Solubility.:DMSO (Slightly, Heated), Methanol (Slightly)
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:123.068413911
Heavy Atom Count:9
Complexity:181

Purity/Quality:

98%, ^*data from raw suppliers

2,6-Dimethyl-4-hydroxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=O)C=C(N1)C
Uses 2,6-Dimethyl-4-hydroxypyridine is a useful synthetic intermediate. It is used in the synthesis of disubstituted pyridinyl-aminohydantoins as selective human BACE1 inhibitors.

Technology Process of 2,6-Dimethyl-4-Hydroxypyridine

There total 12 articles about 2,6-Dimethyl-4-Hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 520-45-6,53488-80-5
Dehydracetic acid

: 13603-44-6
2,6-dimethylpyridin-4-ol

Guidance literature:: With ammonia; In water; at 120 ℃; for 0.333333h; Microwave irradiation;

Reference yield: 50.0%

: 5093-70-9
4-bromo-2,6-dimethylpyridine

: 13603-44-6
2,6-dimethylpyridin-4-ol

Guidance literature:: With syn-benzaldehyde oxime; N¹,N²-bis(thiophen-2-ylmethyl)oxalamide; caesium carbonate; copper(l) chloride; In dimethyl sulfoxide; at 80 ℃; for 20h; Reagent/catalyst; Temperature; Glovebox; Schlenk technique; Sealed tube; Inert atmosphere;
DOI:10.1002/cctc.201900393