N-Trimethylsilylaniline

Base Information

• Chemical Name: N-Trimethylsilylaniline
• CAS No.: 3768-55-6
• Molecular Formula: C9H15NSi
• Molecular Weight: 165.31
• Hs Code.: 2931900090
• European Community (EC) Number: 223-197-7
• DSSTox Substance ID: DTXSID3063174
• Nikkaji Number: J217.664E
• Wikidata: Q81990541
• Mol file: 3768-55-6.mol

Synonyms:N-Trimethylsilylaniline;3768-55-6;Silanamine, 1,1,1-trimethyl-N-phenyl-;Anilinotrimethylsilane;Trimethyl-N-phenylsilylamine;1,1,1-Trimethyl-N-phenylsilanamine;Aniline, TMS derivative;N-(trimethylsilyl)aniline;EINECS 223-197-7;C9H15NSi;N-Phenyltrimethylsilylamine;Phenyl(trimethylsilyl)amine;SCHEMBL49520;ANILINOTRIMETHYLSILANE?;C9-H15-N-Si;DTXSID3063174;1,1,1-Trimethyl-N-phenylsilamine;3-(N,N-Dimethyl)propane sulfonate;N-Phenyl-N-(trimethylsilyl)amine #;MFCD00053663;AKOS006346459;Silylamine, 1,1,1-trimethyl-N-phenyl-;FT-0693057;S19030

Chemical Property of N-Trimethylsilylaniline

Chemical Property:

• Vapor Pressure: 0.243mmHg at 25°C
• Refractive Index: 1.5220
• Boiling Point: 206 °C at 760 mmHg
• PKA: 5.60±0.38(Predicted)
• Flash Point: 78.4 °C
• PSA: 12.03000
• Density: 0.93 g/cm³
• LogP: 3.00640
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 165.097376017
• Heavy Atom Count: 11
• Complexity: 111

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-TRIMETHYLSILYLANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)NC1=CC=CC=C1

Technology Process of N-Trimethylsilylaniline

There total 21 articles about N-Trimethylsilylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.9%

→ N-trimethylsilylaniline (3768-55-6)

Guidance literature:

Reference yield: 56.0%

chloro-trimethyl-silane (75-77-4) → N-trimethylsilylaniline (3768-55-6)

Guidance literature:

With C₆H₅NH₂;

DOI:10.1021/ja01156a097

Reference yield: 22.0%

lithium-N-(phenyl)-trimethylsilylamide → N-trimethylsilylaniline (3768-55-6) + dilithium (Z)-1,4-diphenyltetraaz-2-ene-1,4-diide + Azobenzene (1227476-15-4)

Guidance literature:

With dinitrogen monoxide; In tetrahydrofuran;

DOI:10.1021/acs.inorgchem.8b02129

upstream raw materials:

chloro-trimethyl-silane

aniline

1,1,1,3,3,3-hexamethyl-disilazane

1,1,1-Trimethyl-3,3,3-triaethyl-disilazan

Downstream raw materials:

Trimethylmethoxysilane

(CH₃)2BN(C₆H₅)Si(CH₃)3

N-Triphenylsilylphenylamin

Trianilinodijodphosphoran

Refernces

• 1、 Anbu, Nagaraj,Vijayan, Chellappa,Dhakshinamoorthy, Amarajothi. "A simple and efficient room temperature silylation of diverse functional groups with hexamethyldisilazane using CeO2 nanoparticles as solid catalysts". . . Retrieved 2019/06/08.
• 2、 Kraushaar, Konstantin,Herbig, Marcus,Schmidt, Dana,Wagler, J?rg,B?hme, Uwe,Kroke, Edwin. "Insertion of phenyl isocyanate into monoand diaminosilanes". . p. 909 - 921. Retrieved 2018/01/19.