DL-Ornithino-L-alanine

Base Information

• Chemical Name: DL-Ornithino-L-alanine
• CAS No.: 25693-39-4
• Molecular Formula: C₈H₁₇N₃O₄
• Molecular Weight: 219.241
• Wikidata: Q4337000
• Mol file: 25693-39-4.mol

Synonyms:DL-Ornithino-L-alanine;CHEBI:168570;Q4337000;2-amino-5-[(2-amino-2-carboxyethyl)amino]pentanoic acid

Chemical Property of DL-Ornithino-L-alanine

Chemical Property:

• PSA: 138.67000
• LogP: -0.02850
• XLogP3: -6.7
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 8
• Exact Mass: 219.12190603
• Heavy Atom Count: 15
• Complexity: 222

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(CC(C(=O)O)N)CNCC(C(=O)O)N

Technology Process of DL-Ornithino-L-alanine

There total 9 articles about DL-Ornithino-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-carboxybenzyl-L-ornithine (3304-51-6,118578-06-6) → Nδ-(R,S-2-amino-2-carboxyethyl)-S-ornithine (25693-39-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.4 g / Ac₂O / 20 h / Ambient temperature

2: 80 percent / H₂ / 10 percent Pd/C / methanol / Ambient temperature

3: aq. NaOH / 19 h / Ambient temperature

4: 6 N aq. HCl / 6 h / Heating

With hydrogenchloride; sodium hydroxide; hydrogen; acetic anhydride; palladium on activated charcoal; In methanol;

DOI:10.1021/jf980869p

Reference yield:

For-DL-Orn(Z)-OH (5874-56-6) → Nδ-(R,S-2-amino-2-carboxyethyl)-S-ornithine (25693-39-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / H₂ / 10 percent Pd/C / methanol / Ambient temperature

2: aq. NaOH / 19 h / Ambient temperature

3: 6 N aq. HCl / 6 h / Heating

With hydrogenchloride; sodium hydroxide; hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jf980869p

Reference yield:

L-ornithine hydrochloride (3184-13-2,36630-89-4) → Nδ-(R,S-2-amino-2-carboxyethyl)-S-ornithine (25693-39-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) CuCO₃*Cu(OH)2, 2.) 2.78 N aq. NaOH / 1.) H₂O, reflux, 1 h, 2.) RT, 2 h

2: 1.4 g / Ac₂O / 20 h / Ambient temperature

3: 80 percent / H₂ / 10 percent Pd/C / methanol / Ambient temperature

4: aq. NaOH / 19 h / Ambient temperature

5: 6 N aq. HCl / 6 h / Heating

With hydrogenchloride; sodium hydroxide; hydrogen; acetic anhydride; palladium on activated charcoal; In methanol;

DOI:10.1021/jf980869p

upstream raw materials:

N^α-acetyl-S-ornithine

N^α-formyl-L-ornithine

N-carboxybenzyl-L-ornithine

For-DL-Orn(Z)-OH

Refernces