For-DL-Orn(Z)-OH

Base Information

• Chemical Name: For-DL-Orn(Z)-OH
• CAS No.: 5874-56-6
• Molecular Formula: C₁₄H₁₈N₂O₅
• Molecular Weight: 294.307
• Mol file: 5874-56-6.mol

Synonyms:For-DL-Orn(Z)-OH

Chemical Property of For-DL-Orn(Z)-OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of For-DL-Orn(Z)-OH

There total 1 articles about For-DL-Orn(Z)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formic acid (64-18-6) + N-carboxybenzyl-L-ornithine (3304-51-6,118578-06-6) → For-DL-Orn(Z)-OH (5874-56-6)

Guidance literature:

With acetic anhydride;

Reference yield: 97.0%

For-DL-Orn(Z)-OH (5874-56-6) → N-carboxybenzyl-L-ornithine (3304-51-6,118578-06-6)

Guidance literature:

With mold acylase; In water; triethylamine; at 38 ℃; for 168h; pH 7.4;

DOI:10.1246/bcsj.61.575

Reference yield:

For-DL-Orn(Z)-OH (5874-56-6) → Nε-(benzyloxycarbonyl)ornithine (16937-91-0,118578-06-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent

2: 88 percent / TosOH*H₂O / tetrahydrofuran; H₂O / 9 h / 50 °C

With toluene-4-sulfonic acid; In tetrahydrofuran; water;

DOI:10.1246/bcsj.61.575

upstream raw materials:

formic acid

N-carboxybenzyl-L-ornithine

Downstream raw materials:

N^δ-Benzyloxycarbonyl-N^α-(N^δ-benzyloxycarbonyl-N^α-formyl-L-ornithyl)-L-ornithin-methylester

N-carboxybenzyl-L-ornithine

N^δ-(R,S-2-amino-2-carboxyethyl)-S-ornithine

N^ε-(benzyloxycarbonyl)ornithine

Refernces