Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether

Base Information

• Chemical Name: Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether
• CAS No.: 58109-34-5
• Molecular Formula: C4H2 F6 O
• Molecular Weight: 180.0484992
• Hs Code.: 2909191800
• European Community (EC) Number: 818-872-3
• UNII: D4ONY53P0N
• DSSTox Substance ID: DTXSID10973690
• Nikkaji Number: J733.327G
• Mol file: 58109-34-5.mol

Synonyms:1,1,3,3,3-pentafluoro-2-(fluoromethoxy)-1-propene;Compound A (fluoroether);FDTVE;FDVE-2,2;fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether;pentafluoroisopropenyl fluoromethyl ether

Chemical Property of Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether

Chemical Property:

• Vapor Pressure: 56.7mmHg at 25°C
• Boiling Point: 93.3°Cat760mmHg
• Flash Point: 15.5°C
• PSA: 9.23000
• Density: 1.419g/cm³
• LogP: 2.60040
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 180.00098366
• Heavy Atom Count: 11
• Complexity: 155

Purity/Quality:

95% ^*data from raw suppliers

1,1,3,3,3-Pentafluoro-2-(fluoromethoxy)-1-propene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(OC(=C(F)F)C(F)(F)F)F

Technology Process of Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether

There total 1 articles about Fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sevoflurane (28523-86-6) → 1,1,1,3,3-pentafluoro-2-(fluoromethoxy)-3-methoxypropane (58109-33-4) + fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (58109-34-5) + (Z)-1,3,3,3-Tetrafluoro-2-fluoromethoxy-1-methoxy-propene (111607-91-1) + 1,1,3,3-Tetrafluoro-2-fluoromethoxy-3-methoxy-propene

Guidance literature:

With soda lime; at 120 ℃; for 0.666667h; Product distribution; Mechanism; further time and temperature; also with D₂-sevoflurane;

DOI:10.1016/0022-1139(94)03152-P

Reference yield: 57.0%

fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (58109-34-5) → 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene (206756-25-4)

Guidance literature:

With tetrachloromethane; antimonypentachloride; at 5 ℃; for 1h;

DOI:10.1016/S0022-1139(97)00135-8

Reference yield: 22.5%

sodium methylate (124-41-4) + fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (58109-34-5) → 1,1,1,3,3-pentafluoro-2-(fluoromethoxy)-3-methoxypropane (58109-33-4) + fluoromethyl 1-methoxy-1,3,3,3-tetrafluoro-2-propenyl ether (111607-91-1)

Guidance literature:

at 0 ℃; for 1h;

DOI:10.1016/S0022-1139(00)84149-4

upstream raw materials:

sevoflurane

Downstream raw materials:

1,1,1,3,3-pentafluoro-2-(fluoromethoxy)-3-methoxypropane

fluoromethyl 1-methoxy-1,3,3,3-tetrafluoro-2-propenyl ether

2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene

Refernces