2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene

Base Information

• Chemical Name: 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene
• CAS No.: 206756-25-4
• Molecular Formula: C₄H₂ClF₅O
• Molecular Weight: 196.504
• Mol file: 206756-25-4.mol

Synonyms:

Chemical Property of 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene

Chemical Property:

• Boiling Point: 127.7±40.0 °C(Predicted)
• Density: 1.479±0.06 g/cm3(Predicted)

Purity/Quality:

≥99% ^*data from raw suppliers

2-(Chloromethoxy)-1,1,3,3,3-pentafluoro-1-propene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-(Chloromethoxy)-1,1,3,3,3-pentafluoro-1-propene is a reagent used as a fluoride source in halogen-exchange reactions

Technology Process of 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene

There total 2 articles about 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (58109-34-5) → 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene (206756-25-4)

Guidance literature:

With tetrachloromethane; antimonypentachloride; at 5 ℃; for 1h;

DOI:10.1016/S0022-1139(97)00135-8

Reference yield: 29.0%

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether (26103-07-1) → 2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene (206756-25-4)

Guidance literature:

With methyllithium; In formaldehyde diethyl acetal; monoethylene glycol diethyl ether; at -40 - -31 ℃; Inert atmosphere;

upstream raw materials:

fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether

1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether

Refernces

• 1、 Rozov, Leonid A.,Lessor, Ralph A.,Kudzma, Linas V.,Ramig, Keith. "The fluoromethyl ether sevoflurane as a fluoride source in halogen-exchange reactions 1". . p. 51 - 54. Retrieved 2007/10/03.