Hydroxymethanesulfonic acid

Base Information

• Chemical Name: Hydroxymethanesulfonic acid
• CAS No.: 75-92-3
• Molecular Formula: CH4 O4 S
• Molecular Weight: 112.106
• DSSTox Substance ID: DTXSID8048070
• Nikkaji Number: J258.497B
• Wikidata: Q81984479
• ChEMBL ID: CHEMBL3306384
• Mol file: 75-92-3.mol

Synonyms:formaldehyde bisulfite;formaldehyde bisulfite, monopotassium salt;formaldehyde bisulfite, monosodium salt;formaldehyde sodium bisulfite;hydroxymethanesulfonate, sodium salt;hydroxymethanesulfonic acid;hydroxymethylsulfonate;hydroxymethylsulphonate;sodium hydroxymethanesulfonate

Chemical Property of Hydroxymethanesulfonic acid

Chemical Property:

• PSA: 0.00000
• LogP: 3.81660
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 111.98302978
• Heavy Atom Count: 6
• Complexity: 104

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(O)S(=O)(=O)O

Technology Process of Hydroxymethanesulfonic acid

There total 2 articles about Hydroxymethanesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O3-methanesulfonyl-D-xylose (99116-23-1) → formic acid (64-18-6) + hydroxymethanesulphonic acid (75-92-3) + (S)-3,4-dihydroxy-butyraldehyde (81893-52-9)

Guidance literature:

at 25 ℃; zeitlicher Verlauf der Hydrolyse_.Hydrolysis;

DOI:10.1039/jr9570002690

Reference yield:

sodium thiosulfate → hydroxymethanesulphonic acid (75-92-3) + sulfur (7704-34-9)

Guidance literature:

With formaldehyd; In not given; addition of Na-acetate, Na-hydrogene carbonate or acetic acid-acetate buffer, 40%-formaldehyde added; pH 4.6-8.9;

Reference yield:

hydroxymethanesulphonic acid (75-92-3) + potassium cyanide (151-50-8) + (+/-)-norphenylephrine hydrochloride (4779-94-6) → N-<2-(m-Hydroxyphenyl)-2-hydroxyethyl>aminoacetonitrile

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction; 1.) 8-10 deg C, 2.) water, 3 h;

DOI:10.1007/BF00764685

upstream raw materials:

O³-methanesulfonyl-D-xylose

Downstream raw materials:

(4-arsono-anilino)-methanesulfonic acid

(4-thiosemicarbazonomethyl-anilino)-methanesulfonic acid