Technology Process of 1-Cyclohexene-1-carboxylic acid, 4-(2-methyl-1,3-dioxolan-2-yl)-, ethyl
ester
There total 5 articles about 1-Cyclohexene-1-carboxylic acid, 4-(2-methyl-1,3-dioxolan-2-yl)-, ethyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) ozonized oxygen, 2.) dimethyl sulfide / 1) pyridine, methanol, -78 deg C, 1 h; 2) -78 deg C --> room temperature, 12 h
2: 20.9 g / hydrogen chloride (gas) / 12 h / Heating
3: 1.) p-toluenesulfonic acid, 2.) lithium diisopropylamide / 1) benzene, reflux, 24 h; 2) THF, -78 deg C
With
hydrogenchloride; ozone-containing oxygen; dimethylsulfide; toluene-4-sulfonic acid; lithium diisopropyl amide;
DOI:10.1021/ja00538a029
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) pyridine, methanesulfonyl chloride / 1) 0 deg C, 2 h; 2) room temperature, 3 h
2: 1.) ozonized oxygen, 2.) dimethyl sulfide / 1) pyridine, methanol, -78 deg C, 1 h; 2) -78 deg C --> room temperature, 12 h
3: 20.9 g / hydrogen chloride (gas) / 12 h / Heating
4: 1.) p-toluenesulfonic acid, 2.) lithium diisopropylamide / 1) benzene, reflux, 24 h; 2) THF, -78 deg C
With
pyridine; hydrogenchloride; ozone-containing oxygen; dimethylsulfide; toluene-4-sulfonic acid; methanesulfonyl chloride; lithium diisopropyl amide;
DOI:10.1021/ja00538a029
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 20.9 g / hydrogen chloride (gas) / 12 h / Heating
2: 1.) p-toluenesulfonic acid, 2.) lithium diisopropylamide / 1) benzene, reflux, 24 h; 2) THF, -78 deg C
With
hydrogenchloride; toluene-4-sulfonic acid; lithium diisopropyl amide;
DOI:10.1021/ja00538a029
