4-isopropenylcyclohexene-1-carbonitrile

Base Information

• Chemical Name: 4-isopropenylcyclohexene-1-carbonitrile
• CAS No.: 60188-94-5
• Molecular Formula: C₁₀H₁₃N
• Molecular Weight: 147.22
• Mol file: 60188-94-5.mol

Synonyms:

Chemical Property of 4-isopropenylcyclohexene-1-carbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-isopropenylcyclohexene-1-carbonitrile

There total 6 articles about 4-isopropenylcyclohexene-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

p-mentha-1,8-dien-7-al oxime (138-91-0) → 4-isopropenylcyclohexene-1-carbonitrile (60188-94-5,156555-45-2)

Guidance literature:

With trifluoromethylsulfonic anhydride; Triphenylphosphine oxide; In dichloromethane; 1,2-dichloro-ethane; at 83 ℃; for 0.0833333h;

DOI:10.1021/jo00227a041

Reference yield: 85.0%

perillaldehyde (2111-75-3) → 4-isopropenylcyclohexene-1-carbonitrile (60188-94-5,156555-45-2)

Guidance literature:

With ammonia; oxygen; In tert-Amyl alcohol; at 40 ℃; for 24h; under 750.075 Torr; Green chemistry;

DOI:10.1039/c7gc02627g

Reference yield:

perillartine (30950-27-7,40600-49-5,40600-50-8) → 4-isopropenylcyclohexene-1-carbonitrile (60188-94-5,156555-45-2)

Guidance literature:

With pyridine; methanesulfonyl chloride; Yield given. Multistep reaction; 1) 0 deg C, 2 h; 2) room temperature, 3 h;

DOI:10.1021/ja00538a029

upstream raw materials:

perillartine

p-mentha-1,8-dien-7-al oxime

perillaldehyde

Downstream raw materials:

4-acetylcyclohexane-1-carbonitrile

ethyl 4-acetylcyclohexene-1-carboxylate

ethyl 4-(2-methyl-1,3-dioxolan-2-yl)cyclohexene-1-carboxylate

Ethyl 2--4-(2-methyl-1,3-dioxolan-2-yl)cyclohexane-1-carboxylate

Refernces

• 1、 Hendrickson, James B.,Hussoin, Md. Sajjat. "Seeking the Ideal Dehydrating Reagent". . p. 4137 - 4139. Retrieved 2007/10/02.