Technology Process of Benzene, 2,5-dichloro-1-iodo-3-(methylsulfonyl)-
There total 4 articles about Benzene, 2,5-dichloro-1-iodo-3-(methylsulfonyl)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hypophosphite; sodium iodide; sodium nitrite;
10% palladium on active carbon;
In
tetrahydrofuran; ethanol; water;
at 0 ℃;
for 0.5h;
ice bath;
DOI:10.1016/0045-6535(95)00331-2
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.56 g / NaOH / ethanol; H2O / 1 h / -15 °C / TLC
2: 1.0 g / KNO3 / H2SO4 / 3 h / -60 - 20 °C
3: 0.79 g / sodium iodide; sodium hypophosphite hydrate; sodium nitrite / Pd-C 10 percent / tetrahydrofuran; ethanol; H2O / 0.5 h / 0 °C / ice bath
With
sodium hydroxide; sodium hypophosphite; potassium nitrate; sodium iodide; sodium nitrite;
10% palladium on active carbon;
In
tetrahydrofuran; ethanol; sulfuric acid; water;
1: Addition / 2: Addition / 3: Substitution;
DOI:10.1016/0045-6535(95)00331-2
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.0 g / KNO3 / H2SO4 / 3 h / -60 - 20 °C
2: 0.79 g / sodium iodide; sodium hypophosphite hydrate; sodium nitrite / Pd-C 10 percent / tetrahydrofuran; ethanol; H2O / 0.5 h / 0 °C / ice bath
With
sodium hypophosphite; potassium nitrate; sodium iodide; sodium nitrite;
10% palladium on active carbon;
In
tetrahydrofuran; ethanol; sulfuric acid; water;
1: Addition / 2: Substitution;
DOI:10.1016/0045-6535(95)00331-2