2-Ethylhexyl palmitate

Base Information

• Chemical Name: 2-Ethylhexyl palmitate
• CAS No.: 29806-73-3
• Deprecated CAS: 149659-54-1
• Molecular Formula: C₂₄H₄₈O₂
• Molecular Weight: 368.644
• Hs Code.: 2915709000
• European Community (EC) Number: 249-862-1
• UNII: 2865993309
• DSSTox Substance ID: DTXSID3027958
• Nikkaji Number: J24.704I
• Wikipedia: Ethylhexyl_palmitate
• Mol file: 29806-73-3.mol

Synonyms:2-ethylhexyl palmitate;ethylhexyl palmitate;octyl palmitate;palmitic acid,2-ethylhexyl ester

Chemical Property of 2-Ethylhexyl palmitate

Chemical Property:

• Vapor Pressure: 7.7E-07mmHg at 25°C
• Melting Point: 2 °C
• Refractive Index: 1.449
• Boiling Point: 407.2 °C at 760 mmHg
• Flash Point: 203.7 °C
• PSA: 26.30000
• Density: 0.86 g/cm³
• LogP: 8.22730
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Hexanes (Slightly)
• Water Solubility.: 4.13ng/L at 25℃
• XLogP3: 10.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 21
• Exact Mass: 368.365430770
• Heavy Atom Count: 26
• Complexity: 288

Purity/Quality:

98%, ^*data from raw suppliers

2-Ethylhexyl Palmitate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCC(CC)CCCC
• Description: Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. It is an alternate to silicone-based ingredients offering a 'dry-slip' feel. It helps adjust consistency in skin-care products.Ethylhexyl palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2–50%, depending on the type of formula and desired aesthetics. It improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers. As a solvent, it helps solubilize other ingredients, helping active ingredients more readily penetrate skin. It helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations. There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin. Paula’s Choice Skincare uses either the synthetic or plant-derived form of this ingredient depending on the product.https://www.paulaschoice.com/ingredient-dictionary/emollients/ethylhexyl-palmitate.html
• Uses: Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products. It functions as an emollient, solvent, and fragrance fixative.In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.MoistureAs an emollient, ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin. Emollients also act as lubricants by reducing friction when anything rubs against the skin. Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin. It is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel.While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin. Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions.SolventEthylhexyl palmitate functions as a solvent by helping other ingredients dissolve. Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin.AppearanceAnother function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent. Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation. Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation. Think about even eyeshadow or foundation pigment.FragranceLastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products. A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin.

Technology Process of 2-Ethylhexyl palmitate

There total 2 articles about 2-Ethylhexyl palmitate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.21%

2-Ethylhexyl alcohol (104-76-7) + 1-hexadecylcarboxylic acid (57-10-3) → 2-ethyl hexanol ester of hexadecanoic acid (29806-73-3)

Guidance literature:

With tin (II) oxalate; In cyclohexane; at 150 ℃; for 2.5h; Autoclave; Reflux;

Reference yield:

2-Ethylhexyl alcohol (104-76-7) + dodec-3-ene (2030-83-3) + 1-hexadecylcarboxylic acid (57-10-3) → 4-dodecyl palmitate + 3-dodecyl palmitate + 2-ethyl hexanol ester of hexadecanoic acid (29806-73-3)

Guidance literature:

dodec-3-ene; 1-hexadecylcarboxylic acid; With sulfuric acid; at 55 ℃; for 18h; Inert atmosphere;

2-Ethylhexyl alcohol; at 55 ℃; for 2h; under 10 Torr;

upstream raw materials:

2-Ethylhexyl alcohol

1-hexadecylcarboxylic acid

dodec-3-ene

Refernces

• 1、 -. "BRANCHED-CHAIN ESTERS AND METHODS OF MAKING AND USING THE SAME". Paragraph 0111. . Retrieved 2015/09/28.
• 2、 Miyazawa, Mitsuo,Uematsu, Tosihisa,Kameoka, Hiromu. "WAX COMPOSITION OF SARGASSUM FULVELLUM". . p. 1788 - 1791. Retrieved 2007/10/02.