4-carboxy-1-methylpyridinium

Base Information

• Chemical Name: 4-carboxy-1-methylpyridinium
• CAS No.: 5746-18-9
• Molecular Formula: C7H8NO2+
• Molecular Weight: 173.599
• Mol file: 5746-18-9.mol

Synonyms:

Chemical Property of 4-carboxy-1-methylpyridinium

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-carboxy-1-methylpyridinium

There total 22 articles about 4-carboxy-1-methylpyridinium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-Methyluracil (626-48-2) + C7H8NO2 (36455-39-7) → 1-methyl-4-carboxypyridinium chloride (5746-18-9) + 6-Methyl-1H-pyrimidine-2,4-dione (626-48-2)

Guidance literature:

In water; at 20 ℃; Rate constant; Equilibrium constant; pH 8.6;

Reference yield:

pyridine-4-carboxylic acid (55-22-1) + methyl iodide (74-88-4) → 1-methyl-4-carboxypyridinium chloride (5746-18-9)

Guidance literature:

With sodium hydroxide; Behandeln der Reaktionsloesung mit wss. HCl und einem Anionen-Austauscher;

DOI:10.1021/ja01514a047

Reference yield:

pyridine-4-carboxylic acid (55-22-1) → 1-methyl-4-carboxypyridinium chloride (5746-18-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / methanol / 40 h / 70 °C

2: propylene oxide / H₂O / 72 h

3: hydrochloric acid

With hydrogenchloride; methyloxirane; In methanol; water;

DOI:10.1016/j.molstruc.2006.02.062

upstream raw materials:

pyridine-4-carboxylic acid

methyl iodide

4-(methoxycarbonyl)-1-methylpyridinium iodide

6-Methyluracil

Downstream raw materials:

C₇H₈NO₂

Thymidin-5'-monophosphat

5'-Uridylic Acid

uridine-3'-phosphate

Refernces

• 1、 Korte,Shih. "Degradation of three related bis(pyridinium)aldoximes in aqueous solutions at high concentrations: Examples of unexpectedly rapid amide group hydrolysis". . p. 782 - 786. Retrieved 1993.
• 2、 Steenken,Telo,Novais,Candeias. "One-electron-reduction potentials of pyrimidine bases, nucleosides, and nucleotides in aqueous solution. Consequences for DNA redox chemistry". . p. 4701 - 4709. Retrieved 2007/10/02.