Carteolol

Base Information

• Chemical Name: Carteolol
• CAS No.: 51781-06-7
• Molecular Formula: C16H24 N2 O3
• Molecular Weight: 292.378
• Hs Code.: 2933790090
• UNII: 8NF31401XG
• DSSTox Substance ID: DTXSID3022746
• Nikkaji Number: J13.087G
• Wikipedia: Carteolol
• Wikidata: Q546434
• NCI Thesaurus Code: C65291
• RXCUI: 2116
• Pharos Ligand ID: T3XURCZ3344T
• Metabolomics Workbench ID: 42862
• ChEMBL ID: CHEMBL839
• Mol file: 51781-06-7.mol

Synonyms:Carteolol;Carteolol Hydrochloride;Carteolol Monohydrochloride;Hydrochloride, Carteolol;Monohydrochloride, Carteolol;OPC 1085;OPC-1085;OPC1085

Chemical Property of Carteolol

Chemical Property:

• Refractive Index: 1.5800 (estimate)
• Boiling Point: 518.6 °C at 760 mmHg
• PKA: 13.84±0.20(Predicted)
• Flash Point: 267.4 °C
• PSA: 70.59000
• Density: 1.13 g/cm³
• LogP: 2.22800
• XLogP3: 1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 292.17869263
• Heavy Atom Count: 21
• Complexity: 354

Purity/Quality:

99%, ^*data from raw suppliers

CARTEOLOL 99 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O
• Recent EU Clinical Trials: EFFECTS OF PROSTAGLANDIN COMPOUNDS ON CONJUNTIVAL MELANOGENESIS: AN IMPRESSION CITOLOGY AND TYROSINASE MARKERS STUDY
• Recent NIPH Clinical Trials: Investigation on the Efficacy and Safety of night instillation of Carteolol/Latanoprost Combination Ophthalmic Solution
• Therapeutic Function: Beta-adrenergic blocker

Technology Process of Carteolol

There total 2 articles about Carteolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

carteolol hydrochloride (51781-21-6) → carteolol (51781-06-7)

Guidance literature:

With potassium carbonate; In water;

DOI:10.1016/j.ejmech.2009.10.017

Reference yield:

→ carteolol (51781-06-7)

Guidance literature:

5-subst. Carbostyril I, tert-Butylamin;

DOI:10.1021/jm00251a013

Reference yield: 97.0%

carteolol (51781-06-7) + C73H69N7O21P3S3(1+)*Cl(1-) → 6C16H24N2O3*C73H69N7O21P3S3(1+)*Cl(1-)

Guidance literature:

In water; for 24h;

DOI:10.1016/j.ejmech.2009.10.017

upstream raw materials:

carteolol hydrochloride

Downstream raw materials:

-(+)-carteolol

-(-)-carteolol

Refernces

• 1、 -. "The illumination optical system, the exposure device and method of manufacturing the device". . . Retrieved 2007/10/05.
• 2、 -. "THERAPY FOR COMPLICATIONS OF DIABETES". . . Retrieved 2009/07/02.