2-METHYL-2H-BENZOTRIAZOLE

Base Information

• Chemical Name: 2-METHYL-2H-BENZOTRIAZOLE
• CAS No.: 16584-00-2
• Molecular Formula: C7H7 N3
• Molecular Weight: 133.153
• Hs Code.: 2933990090
• Mol file: 16584-00-2.mol

Synonyms:2,1,3-Benzotriazole,2-methyl- (4CI); 2-Methyl-2H-benzotriazole; 2-Methylbenzotriazole; NSC 11744

Chemical Property of 2-METHYL-2H-BENZOTRIAZOLE

Chemical Property:

• Vapor Pressure: 0.0213mmHg at 25°C
• Boiling Point: 250.8°Cat760mmHg
• PKA: 2.24±0.30(Predicted)
• Flash Point: 105.5°C
• PSA: 30.71000
• Density: 1.24g/cm³
• LogP: 0.96830

Purity/Quality:

99% ^*data from raw suppliers

2-Methyl-2H-1,2,3-benzotriazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-2H-BENZOTRIAZOLE

There total 20 articles about 2-METHYL-2H-BENZOTRIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1H-benzotriazole-1-carboxylic acid methyl ester (86298-22-8) → 2-methylbenzotriazole (16584-00-2) + 1-methyl-1H-benzo[d][1,2,3]triazole (13351-73-0)

Guidance literature:

at 120 ℃; Title compound not separated from byproducts;

DOI:10.1002/poc.610061007

Reference yield: 60.0%

1,2,3-Benzotriazole (95-14-7,27556-51-0) + methyl iodide (74-88-4) → 2-methylbenzotriazole (16584-00-2) + 1-methyl-1H-benzo[d][1,2,3]triazole (13351-73-0)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; for 0.5h;

DOI:10.1016/j.ejmech.2016.10.005

Reference yield: 59.0%

Dimethyl oxalate (553-90-2) + 1,2,3-Benzotriazole (95-14-7,27556-51-0) → 2-methylbenzotriazole (16584-00-2) + 1-methyl-1H-benzo[d][1,2,3]triazole (13351-73-0)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; Heating;

DOI:10.1016/S0040-4020(01)87933-3

upstream raw materials:

diazomethane

1,2,3-Benzotriazole

1H-benzotriazole-1-carboxylic acid methyl ester

1,2-dimethyl-benzotriazolium; iodide

Downstream raw materials:

2-methyl-2H-benzotriazole-5-sulfonic acid [5-bromo-2-(piperidine-1-carbonyl)-phenyl]-amide

2-methyl-2H-benzotriazole-4-sulfonic acid [5-bromo-2-(piperidine-1-carbonyl)-phenyl]-amide

2-methyl-2H-benzotriazole-5-sulfonyl chloride

2-methyl-2H-benzotriazole-4-sulfonyl chloride

Refernces

• 1、 Carta, Antonio,Piras, Sandra,Boatto, Gianpiero,Paglietti, Giuseppe. "1H,6H-Triazolo[4,5-e]benzotriazole-3-oxides and 5,5′-(Z)-diazene-1,2-diylbis(2-methyl-2H-1,2,3-benzotriazole) derived from chloronitrobenzotriazoles and hydrazine". . p. 2471 - 2481. Retrieved 2007/10/03.
• 2、 Kurenkov, A. A.,Pevzner, M. S.. "Oxidative Alkylation of Azoles. IV. Reaction of N-Halo- and N-Nitrobenzotriazoles with Methyl Iodide". . p. 1122 - 1124. Retrieved 2007/10/03.