Benzoic acid, 2-bromo-5-ethoxy-, methyl ester

Base Information

• Chemical Name: Benzoic acid, 2-bromo-5-ethoxy-, methyl ester
• CAS No.: 765944-34-1
• Molecular Formula: C10H11BrO3
• Molecular Weight: 259.09700
• Mol file: 765944-34-1.mol

Synonyms:5-ethoxy-2-bromo-benzoic acid methyl ester;5-Aethoxy-2-brom-benzoesaeure-methylester;Benzoic acid,2-bromo-5-ethoxy-,methyl ester;2-bromo-5-ethoxybenzoic acid methyl ester;

Chemical Property of Benzoic acid, 2-bromo-5-ethoxy-, methyl ester

Chemical Property:

• PSA: 35.53000
• LogP: 2.63440

Purity/Quality:

99% ^*data from raw suppliers

Methyl 2-bromo-5-ethoxybenzoate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 2-bromo-5-ethoxy-, methyl ester

There total 2 articles about Benzoic acid, 2-bromo-5-ethoxy-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl iodide (75-03-6) + methyl 3-hydroxy-6-bromobenzoate (154607-00-8) → 5-ethoxy-2-bromo-benzoic acid methyl ester (765944-34-1)

Guidance literature:

methyl 3-hydroxy-6-bromobenzoate; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 1h;

ethyl iodide; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 3h; Product distribution / selectivity;

Reference yield:

methanol (67-56-1) + 5-ethoxy-2-bromo-benzoic acid (120890-75-7) → 5-ethoxy-2-bromo-benzoic acid methyl ester (765944-34-1)

Guidance literature:

With sulfuric acid;

Reference yield:

5-ethoxy-2-bromo-benzoic acid methyl ester (765944-34-1) → 5-ethoxy-2-bromo-benzoic acid (120890-75-7)

Guidance literature:

5-ethoxy-2-bromo-benzoic acid methyl ester; With lithium hydroxide; water; In tetrahydrofuran; for 96h;

With hydrogenchloride; In water; Product distribution / selectivity;

upstream raw materials:

methanol

5-ethoxy-2-bromo-benzoic acid

ethyl iodide

methyl 3-hydroxy-6-bromobenzoate

Downstream raw materials:

5-ethoxy-2-bromo-benzoic acid

Refernces