1,11-Dodecanediol

Base Information

• Chemical Name: 1,11-Dodecanediol
• CAS No.: 80158-99-2
• Molecular Formula: C12H26O2
• Molecular Weight: 202.337
• Mol file: 80158-99-2.mol

Synonyms:

Chemical Property of 1,11-Dodecanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,11-Dodecanediol

There total 2 articles about 1,11-Dodecanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-dodecyl alcohol (112-53-8) → 1,12-dodecandiol (5675-51-4) + Dodecane-2,12-diol (80158-99-2)

Guidance literature:

With 2,3,4,5,6-pentahydroxy-hexanal; cytochrome b5; glucose dehydrogenase from Bacillus megaterium; human cytochrome P₄₅₀ monooxygenase; rat cytochrome P₄₅₀ reductase; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; NADPH; superoxide dismutase; catalase from bovine liver; In aq. phosphate buffer; dimethyl sulfoxide; at 30 ℃; pH=7.5; Reagent/catalyst; Enzymatic reaction;

DOI:10.1016/j.abb.2019.108216

Reference yield:

1-dodecyl alcohol (112-53-8) → 1,10-dihydroxydodecane (39516-27-3) + dodecane-1,4-diol (38146-95-1) + 1,4,9-dodecane triol + Dodecane-2,12-diol (80158-99-2)

Guidance literature:

With glucose dehydrogenase from Bacillus megaterium; cytochrome P₄₅₀ monooxygenase CYP₅₀₅E₃ from Aspergillus terreus; nicotinamide adenine dinucleotide; In aq. phosphate buffer; at 25 ℃; for 24h; regioselective reaction; Catalytic behavior; Enzymatic reaction;

DOI:10.1002/anie.202001055

Reference yield:

Dodecane-2,12-diol (80158-99-2) → 11-oxododecanoic acid (2388-78-5)

Guidance literature:

With sulfuric acid; chromium(VI) oxide; In water; acetone; at 20 ℃;

upstream raw materials:

1-dodecyl alcohol

Downstream raw materials:

11-oxododecanoic acid

Refernces

• 1、 Maseme, Mpeyake Jacob,Opperman, Diederik Johannes,Pennec, Alizé,Smit, Martha Sophia,van Marwijk, Jacqueline. "CYP505E3: A Novel Self-Sufficient ω-7 In-Chain Hydroxylase". supporting information. p. 10359 - 10362. Retrieved 2020/04/23.