Technology Process of 1,4-Dioxaspiro[4.5]decan-8-one, 6,7-dimethyl-
There total 1 articles about 1,4-Dioxaspiro[4.5]decan-8-one, 6,7-dimethyl- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; toluene-4-sulfonic acid;
In
acetone;
for 2h;
Yield given. Yields of byproduct given;
Heating;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 86 percent / Na, isopropyl alcohol / toluene / 1 h / Heating
2: 85 percent / 0.5N HCl / tetrahydrofuran / 1 h / Heating
3: 97 percent / pyridinium p-toluenesulfonate / CH2Cl2 / 20 h / Ambient temperature
4: 60 percent NaH (mineraloil) / benzene / 20 h / Ambient temperature
5: 1.)p-toluenesulfonyl chloride, pyridine / 1.) 0 deg C, 3 h, 2.) 0 deg C, 20 h
6: 1.) potassium tert-butoxide / 1.) t-BuOH, room temp., 1 h, 2.) 30 min.
With
pyridine; hydrogenchloride; potassium tert-butylate; sodium; pyridinium p-toluenesulfonate; sodium hydride; p-toluenesulfonyl chloride; isopropyl alcohol;
In
tetrahydrofuran; dichloromethane; toluene; benzene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 86 percent / Na, isopropyl alcohol / toluene / 1 h / Heating
2: 85 percent / 0.5N HCl / tetrahydrofuran / 1 h / Heating
With
hydrogenchloride; sodium; isopropyl alcohol;
In
tetrahydrofuran; toluene;