Tricyclo(3.3.1.13,7)decan-1-acetamide

Base Information

• Chemical Name: Tricyclo(3.3.1.13,7)decan-1-acetamide
• CAS No.: 19026-73-4
• Molecular Formula: C12H19NO
• Molecular Weight: 193.289
• European Community (EC) Number: 242-762-9
• DSSTox Substance ID: DTXSID50172509
• Nikkaji Number: J216.774C
• Wikidata: Q83042621
• Mol file: 19026-73-4.mol

Synonyms:2-(1-adamantyl)acetamide;Tricyclo(3.3.1.13,7)decan-1-acetamide;19026-73-4;1-adamantaneacetamide;EINECS 242-762-9;Tricyclo[3.3.1.13,7]decan-1-acetamide;Tricyclo[3.3.1.13,7]decane-1-acetamide;adamantylacetamide;adamant-1-yl acetamide;Maybridge1_006634;Oprea1_333178;1-(Carbamoylmethyl)adamantane;SCHEMBL1478949;HMS560F12;DTXSID50172509;2-ADAMANTAN-1-YL-ACETAMIDE;MFCD00220381;AKOS001022308;Tricyclo(3.3.1.1(3,7)-)decane-1-acetamide;AE-848/00964052;SR-01000396848;SR-01000396848-1;Z33546612

Chemical Property of Tricyclo(3.3.1.13,7)decan-1-acetamide

Chemical Property:

• Vapor Pressure: 1.9E-05mmHg at 25°C
• Boiling Point: 362.7°Cat760mmHg
• Flash Point: 173.1°C
• Density: 1.12g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 193.146664230
• Heavy Atom Count: 14
• Complexity: 230

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2CC3CC1CC(C2)(C3)CC(=O)N

Technology Process of Tricyclo(3.3.1.13,7)decan-1-acetamide

There total 9 articles about Tricyclo(3.3.1.13,7)decan-1-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl (1-adamantyl)acetimidate hydrochloride → 2-(1-adamantyl)acetamide (19026-73-4)

Guidance literature:

at 205 - 210 ℃;

DOI:10.1023/A:1013919230608

Reference yield: 90.6%

adamantan-2-ylacetic acid (26082-22-4) → 1-adamantaneacetamide (19026-73-4)

Guidance literature:

adamantan-2-ylacetic acid; With hexafluoropropene-diethylamine adduct;

With ammonia; In water; at 20 ℃;

Reference yield:

(adamant-1-yl)-acetic acid (4942-47-6) + acetonitrile (75-05-8,26809-02-9) → N-(adamantan-1-yl-acetyl)-acetamide + 1-Carboxymethyladamantane nitrile (16269-13-9) + 2-(1-adamantyl)acetamide (19026-73-4)

Guidance literature:

With sulfuric acid; at 40 ℃; for 18h;

DOI:10.1055/s-2005-871967

upstream raw materials:

1-adamantylacetyl chloride

(adamant-1-yl)-acetic acid

acetonitrile

1-Carboxymethyladamantane nitrile

Downstream raw materials:

1-Carboxymethyladamantane nitrile

2-(1-adamantyl)ethanamine

1-adamantanecarbonitrile

Refernces

• 1、 -. "Corresponding amine nitrile and method of manufacturing thereof". Paragraph 0138; 0139; 0140; 0149; 0150. . Retrieved 2018/05/07.
• 2、 Mlinari?-Majerski, Kata,Margeta, Renato,Veljkovi?, Jelena. "A facile and efficient one-pot synthesis of nitriles from carboxylic acids". . p. 2089 - 2091. Retrieved 2007/10/03.