Benzoyl chloride, 4-amino- (9CI)

Base Information

• Chemical Name: Benzoyl chloride, 4-amino- (9CI)
• CAS No.: 16106-38-0
• Molecular Formula: C7H6ClNO
• Molecular Weight: 155.584
• Hs Code.: 2922499990
• Mol file: 16106-38-0.mol

Synonyms:Benzoylchloride, p-amino-;4-Aminobenzoyl chloride;p-Aminobenzoylchloride;

Chemical Property of Benzoyl chloride, 4-amino- (9CI)

Chemical Property:

• Vapor Pressure: 0.00288mmHg at 25°C
• Refractive Index: 1.605
• Boiling Point: 285 °C at 760 mmHg
• PKA: 1.21±0.10(Predicted)
• Flash Point: 126.1 °C
• PSA: 43.09000
• Density: 1.317g/cm³
• LogP: 2.22900

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Aminobenzoyl chloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoyl chloride, 4-amino- (9CI)

There total 4 articles about Benzoyl chloride, 4-amino- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 4-aminobenzoyl chloride (16106-38-0)

Guidance literature:

With thionyl chloride; at 50 - 60 ℃; for 2h; Inert atmosphere;

Reference yield: 85.0%

4-nitro-benzoyl chloride (122-04-3) → 4-aminobenzoyl chloride (16106-38-0)

Guidance literature:

With sodium tetrahydroborate; water; at 20 ℃; for 1.08333h;

DOI:10.1016/j.jssc.2021.122381

Reference yield:

thionyl chloride (7719-09-7) + 4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 4-aminobenzoyl chloride (16106-38-0)

Guidance literature:

upstream raw materials:

4-amino-benzoic acid

thionyl chloride

4-nitro-benzoyl chloride

Downstream raw materials:

ethyl (4-aminobenzoyl)cyanoacetate

O^2'_,O3'_,O5'-tris-(4-amino-benzoyl)-adenosine

4-amino-N,N-dimethylbenzamide

p-Aminohippuric acid

Refernces

• 1、 -. "AROMATIC AMINE COMPOUND, CURING AGENT FOR EPOXY COMPOUND, CURABLE COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING CURED PRODUCT, AND METHOD FOR PRODUCING AROMATIC AMINE COMPOUND". Paragraph 0117. . Retrieved 2021/05/07.
• 2、 Bayliss, Richard,Boxall, Kathy,Carbain, Benoit,Coxon, Christopher R.,Fry, Andrew M.,Golding, Bernard T.,Griffin, Roger J.,Hardcastle, Ian R.,Harnor, Suzannah J.,Mas-Droux, Corine,Matheson, Christopher J.,Newell, David R.,Richards, Mark W.,Sivaprakasam, Mangaleswaran,Turner, David,Cano, Céline. "2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase". supporting information. p. 707 - 731. Retrieved 2020/08/24.