2-(Pyrazin-2-yl)ethanamine

Base Information

• Chemical Name: 2-(Pyrazin-2-yl)ethanamine
• CAS No.: 5321-59-5
• Molecular Formula: C6H9 N3
• Molecular Weight: 123.16
• Hs Code.: 2933990090
• European Community (EC) Number: 828-112-2
• DSSTox Substance ID: DTXSID70389995
• Wikidata: Q82186336
• Mol file: 5321-59-5.mol

Synonyms:5321-59-5;2-(Pyrazin-2-yl)ethanamine;2-Pyrazin-2-yl-ethylamine;2-(pyrazin-2-yl)ethan-1-amine;2-pyrazin-2-ylethanamine;(2-Pyrazin-2-ylethyl)amine;Pyrazineethanamine;2-pyrazin-2-ylethylamine;SCHEMBL2308662;AMY4378;DTXSID70389995;WJNJQSDKFXGALV-UHFFFAOYSA-N;MFCD05863867;AKOS000538950;AB22666;AT22557;(2-Pyrazin-2-ylethyl)amine, AldrichCPR;BS-13088;BB 0250750;CS-0139251;FT-0703360;EN300-41585;A870792;J-506574

Chemical Property of 2-(Pyrazin-2-yl)ethanamine

Chemical Property:

• Vapor Pressure: 0.105mmHg at 25°C
• Boiling Point: °Cat760mmHg
• PKA: 9.10±0.10(Predicted)
• Flash Point: °C
• PSA: 51.80000
• Density: 1.17g/cm³
• LogP: 0.67810
• Storage Temp.: 2-8°C
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 123.079647300
• Heavy Atom Count: 9
• Complexity: 74.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Pyrazin-2-yl-ethylamine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(C=N1)CCN

Technology Process of 2-(Pyrazin-2-yl)ethanamine

There total 5 articles about 2-(Pyrazin-2-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ 2-(2-pyrazinyl)ethanamine (5321-59-5)

Guidance literature:

Reference yield:

3-pyrazinyl-propionic acid amide (94777-13-6) → 2-(2-pyrazinyl)ethanamine (5321-59-5)

Guidance literature:

With sodium hypochlorite;

DOI:10.1021/ja01164a061

Reference yield:

3-(2-pyrazinyl)propanoic acid (6705-34-6) → 2-(2-pyrazinyl)ethanamine (5321-59-5)

Guidance literature:

Multi-step reaction with 2 steps

2: aqueous NaClO

With sodium hypochlorite;

DOI:10.1021/ja01164a061

upstream raw materials:

3-pyrazinyl-propionic acid amide

3-(2-pyrazinyl)propanoic acid

Downstream raw materials:

2-[4-({(E)-[ethyl(methyl)amino]methylidene}amino)-2,5-dimethylbenzyl]-N-[2-(pyrazin-2-yl)ethyl]-1,3-thiazole-4-carboxamide

3-oxo-2-(2-pyrazin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide

Refernces

• 1、 -. "Epoxysuccinamide derivative or salt thereof". . . Retrieved 2008/06/13.