3-(Pyrazin-2-yl)propanoic acid

Base Information

• Chemical Name: 3-(Pyrazin-2-yl)propanoic acid
• CAS No.: 6705-34-6
• Molecular Formula: C7H8N2O2
• Molecular Weight: 152.15
• Hs Code.: 2933990090
• European Community (EC) Number: 853-295-0
• DSSTox Substance ID: DTXSID70590781
• Wikidata: Q82484421
• Mol file: 6705-34-6.mol

Synonyms:3-(Pyrazin-2-yl)propanoic acid;6705-34-6;3-(2-pyrazinyl)propanoic acid;3-pyrazin-2-ylpropanoic acid;2-Pyrazinepropanoic acid;MFCD09054674;3-Pyrazin-2-yl-propionic acid;2,5-(b-carboxyethyl)pyrazine;3-(Pyrazin-2-yl)propanoicacid;SCHEMBL1648472;DTXSID70590781;AKOS006282555;DA-41743;LS-11592;SY131796;EN300-102615;N12623;J-510944;Z1198184629

Chemical Property of 3-(Pyrazin-2-yl)propanoic acid

Chemical Property:

• Vapor Pressure: 0.000373mmHg at 25°C
• Refractive Index: 1.55
• Boiling Point: 304.8°C at 760 mmHg
• Flash Point: 138.2°C
• PSA: 63.08000
• Density: 1.269g/cm³
• LogP: 0.49380
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 152.058577502
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-(pyrazin-2-yl)propanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(C=N1)CCC(=O)O

Technology Process of 3-(Pyrazin-2-yl)propanoic acid

There total 4 articles about 3-(Pyrazin-2-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

→ 3-(2-pyrazinyl)propanoic acid (6705-34-6)

Guidance literature:

Reference yield:

tert-butyl 3-(pyrazin-2-yl)propanoate (165530-42-7) → 3-(2-pyrazinyl)propanoic acid (6705-34-6)

Guidance literature:

With water; trifluoroacetic acid; at 20 ℃; for 1h;

Reference yield:

→ 3-(2-pyrazinyl)propanoic acid (6705-34-6)

Guidance literature:

With sodium hydroxide; nickel; Hydrogenation;

DOI:10.1021/ja01164a061

upstream raw materials:

tert-butyl 3-(pyrazin-2-yl)propanoate

Downstream raw materials:

2-(2-pyrazinyl)ethanamine

Refernces

• 1、 -. "Bicyclic fibrinogen antagonists". . . Retrieved 2008/06/13.