sodium N-acetylsulphanilate

Base Information

• Chemical Name: sodium N-acetylsulphanilate
• CAS No.: 6034-54-4
• Molecular Formula: C8H9 N O4 S . Na
• Molecular Weight: 237.212
• Hs Code.: 2924299090
• Mol file: 6034-54-4.mol

Synonyms:Benzenesulfonicacid, 4-(acetylamino)-, monosodium salt (9CI); Sulfanilic acid, N-acetyl-,monosodium salt (8CI); N-Acetylsulfanilic acid sodium salt; Sodiump-acetamidobenzenesulfonate

Chemical Property of sodium N-acetylsulphanilate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 98.17000
• Density: 1.481g/cm³
• LogP: 2.49450

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium N-acetylsulphanilate

There total 4 articles about sodium N-acetylsulphanilate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

pyridinium 4-acetamidobenzenesulfonate (54981-38-3) → sodium p-acetaminobenzenesulfonate (6034-54-4)

Guidance literature:

With sodium hydroxide; In water; at 0 - 20 ℃;

DOI:10.1021/acs.jmedchem.0c02042

Reference yield:

sodium sulfanilate (515-74-2) → sodium p-acetaminobenzenesulfonate (6034-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 2 h / Inert atmosphere

2: sodium hydroxide / water / 0 - 20 °C

With sodium hydroxide; In water;

DOI:10.1021/acs.jmedchem.0c02042

Reference yield:

acetic anhydride (108-24-7) + sodium sulfanilate (515-74-2) → sodium p-acetaminobenzenesulfonate (6034-54-4)

Guidance literature:

at 140 ℃;

upstream raw materials:

acetic anhydride

sodium sulfanilate

acetic acid

pyridinium 4-acetamidobenzenesulfonate

Downstream raw materials:

p-(acetylamino)benzoic acid

p-acetylaminobenzenesulfonamide

sulfanilamide

Refernces