TRISALICYLIC ACID (100 MG)

Base Information

• Chemical Name: TRISALICYLIC ACID (100 MG)
• CAS No.: 85531-17-5
• Molecular Formula: C21H14O7
• Molecular Weight: 378.338
• Hs Code.: 2918230000
• Mol file: 85531-17-5.mol

Synonyms:Benzoic acid,2-[(2-hydroxybenzoyl)oxy]-,2-carboxyphenyl ester;trisalicylide;

Chemical Property of TRISALICYLIC ACID (100 MG)

Chemical Property:

• Melting Point: 144 - 146oC
• PSA: 110.13000
• LogP: 3.52880
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Tri-Salicylic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Tri-Salicylic Acid is a product of the thermal decomposition of aspirin.

Technology Process of TRISALICYLIC ACID (100 MG)

There total 3 articles about TRISALICYLIC ACID (100 MG) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

phenyl phenylacetate (722-01-0) + phenyl Salicylate (118-55-8) → 4-hydroxy-3-phenylcoumarin (1786-05-6) + 2-Phenylacetoxy-benzoic acid phenyl ester (114832-89-2) + 6-[1-Phenyl-meth-(Z)-ylidene]-6H-5,12-dioxa-chrysen-11-one (114832-91-6) + tri-salicylic acid (85531-17-5)

Guidance literature:

In diphenylether; at 270 ℃; for 0.5h; Further byproducts given;

Reference yield: 13.0%

phenylacetic acid (103-82-2) + phenyl Salicylate (118-55-8) → phenyl phenylacetate (722-01-0) + 2-Phenylacetoxy-benzoic acid phenyl ester (114832-89-2) + 6-[1-Phenyl-meth-(Z)-ylidene]-6H-5,12-dioxa-chrysen-11-one (114832-91-6) + tri-salicylic acid (85531-17-5)

Guidance literature:

In diphenylether; at 270 ℃; for 0.5h; Further byproducts given;

Reference yield:

aspirin (50-78-2,98201-60-6) → 2-hydroxy-benzoic acid, 2-carboxyphenyl ester (552-94-3) + acetylsalicylsalicylic acid (530-75-6) + 2-{2-[2-(2-acetoxy-benzoyloxy)-benzoyloxy]-benzoyloxy}-benzoic acid (85539-30-6) + tri-salicylic acid (85531-17-5) + C23H16O8 (85531-16-4) + salicylic acid (69-72-7,25496-36-0,8052-31-1)

Guidance literature:

With magnesium carbonate; at 85 ℃; for 2h; Product distribution; also in benzene or toluene with or without magnesium carbonate;

DOI:10.1002/jps.2600720331

upstream raw materials:

phenylacetic acid

phenyl Salicylate

phenyl phenylacetate

aspirin

Downstream raw materials:

C₂₃H₁₆O₈

Refernces

• 1、 Reepmeyer. "Thermal decomposition of aspirin: Formation of linear oligomeric salicylate esters". . p. 322 - 323. Retrieved 2007/10/02.