Tetraphenylmethane

Base Information

• Chemical Name: Tetraphenylmethane
• CAS No.: 630-76-2
• Molecular Formula: C25H20
• Molecular Weight: 320.434
• Hs Code.: 29029090
• European Community (EC) Number: 211-144-0
• NSC Number: 43332
• UNII: CM2Q9C446P
• DSSTox Substance ID: DTXSID30212215
• Nikkaji Number: J53.692J
• Wikipedia: Tetraphenylmethane
• Wikidata: Q420710
• Mol file: 630-76-2.mol

Synonyms:tetraphenylmethane

Chemical Property of Tetraphenylmethane

Chemical Property:

• Appearance/Colour: White to pink powder or needle
• Vapor Pressure: 2.93E-07mmHg at 25°C
• Melting Point: 281-286 °C
• Refractive Index: 1.62
• Boiling Point: 431.8 °C at 760 mmHg
• Flash Point: 212.5 °C
• PSA: 0.00000
• Density: 1.082 g/cm³
• LogP: 6.06930
• Storage Temp.: 2-8°C
• Solubility.: insoluble in Ether,Alcohol
• Water Solubility.: Insoluble in water.
• XLogP3: 7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 320.156500638
• Heavy Atom Count: 25
• Complexity: 295

Purity/Quality:

99% ^*data from raw suppliers

Tetraphenylmethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 40
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4
• Uses: Tetraphenylmethane is used to prepare a tetrapyridone tecton, which forms a diamondoid network with large internal chambers. It is also used in the preparation of 1-{4-[tris-(4-acetyl-phenyl)-methyl]-phenyl}-ethanone by Friedel-Crafts acylation reaction with acetyl chloride using aluminum chloride as catalyst.

Technology Process of Tetraphenylmethane

There total 99 articles about Tetraphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-tritylaniline hydrochloride (945018-87-1) → tetraphenylmethane (630-76-2)

Guidance literature:

4-tritylaniline hydrochloride; With sulfuric acid; isopentyl nitrite; In N,N-dimethyl-formamide; at -15 ℃; for 1h;

With hypophosphorous acid; In N,N-dimethyl-formamide; at 50 ℃; for 4h;

DOI:10.1002/ejoc.202001415

Reference yield: 95.0%

trityl chloride (76-83-5) + aniline (62-53-3) → tetraphenylmethane (630-76-2)

Guidance literature:

trityl chloride; aniline; at 190 ℃; for 0.25h;

With sulfuric acid; isopentyl nitrite; In N,N-dimethyl-formamide; at -15 ℃; for 1h;

With hypophosphorous acid; In N,N-dimethyl-formamide; at 50 ℃;

DOI:10.1021/jacs.9b10884

Reference yield: 92.4%

4-tritylaniline (22948-06-7) → tetraphenylmethane (630-76-2)

Guidance literature:

4-tritylaniline; With sulfuric acid; isopentyl nitrite; In N,N-dimethyl-formamide; at -10 ℃; for 1h;

With hypophosphorous acid; In water; N,N-dimethyl-formamide;

DOI:10.1039/d1ra02938j

upstream raw materials:

1,4-dioxane

trityl chloride

bromobenzene

triphenylmethyl sodium

Downstream raw materials:

(2-cyclohexen-1-ylmethyl)-benzene

dicyclohexylmethane

tricyclohexylmethane

tetrakis(4-nitrophenyl)methane

Refernces

• 1、 Kryger et al.. "". . p. 7589. Retrieved 1977.
• 2、 Matt, Yannick,Wessely, Isabelle,Gramespacher, Lisa,Tsotsalas, Manuel,Br?se, Stefan. "Rigid Multidimensional Alkoxyamines: A Versatile Building Block Library". supporting information. p. 239 - 245. Retrieved 2020/12/17.
• 3、 Angeli, Giasemi K.,Batzavali, Danai,Mavronasou, Katerina,Tsangarakis, Constantinos,Stuerzer, Tobias,Ott, Holger,Trikalitis, Pantelis N.. "Remarkable Structural Diversity between Zr/Hf and Rare-Earth MOFs via Ligand Functionalization and the Discovery of Unique (4, 8)-c and (4, 12)-connected Frameworks". . p. 15986 - 15994. Retrieved 2020/10/18.