1,2,4-Benzenetris(carboxylic acid ethyl) ester

Base Information

• Chemical Name: 1,2,4-Benzenetris(carboxylic acid ethyl) ester
• CAS No.: 14230-18-3
• Molecular Formula: C15H18 O6
• Molecular Weight: 294.304
• Hs Code.: 2917399090
• Mol file: 14230-18-3.mol

Synonyms:1,2,4-Benzenetricarboxylicacid, triethyl ester (7CI,8CI,9CI); 1,2,4-Tricarboethoxybenzene;1,2,4-Tris(ethoxycarbonyl)benzene; Triethyl 1,2,4-benzenetricarboxylate;Triethyl trimellitate

Chemical Property of 1,2,4-Benzenetris(carboxylic acid ethyl) ester

Chemical Property:

• PSA: 78.90000
• LogP: 2.21670

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,4-Benzenetris(carboxylic acid ethyl) ester

There total 16 articles about 1,2,4-Benzenetris(carboxylic acid ethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

propynoic acid ethyl ester (623-47-2) → triethyl benzene-1,2,4-tricarboxylate (14230-18-3)

Guidance literature:

With copper dichloride; palladium dichloride; In methanol; carbon dioxide; at 40 ℃; for 12h; under 120012 Torr;

DOI:10.1002/ejoc.200300299

Reference yield: 92.0%

propynoic acid ethyl ester (623-47-2) → triethyl benzene-1,3,5-tricarboxylate (4105-92-4) + triethyl benzene-1,2,4-tricarboxylate (14230-18-3)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; triphenylphosphine; In toluene; at 23 ℃; for 2h; Inert atmosphere;

Reference yield: 56.0%

(E)-4-(Triphenyl-λ5-phosphanylidene)-pent-2-enedioic acid diethyl ester (119930-16-4) + propynoic acid ethyl ester (623-47-2) → triethyl benzene-1,3,5-tricarboxylate (4105-92-4) + triethyl benzene-1,2,4-tricarboxylate (14230-18-3) + 2,4-diethoxycarbonyl-6-triphenylphosphoniumphenoxide + 1,3,5-triethoxycarbonylpenta-2,4-dienylidenetriphenylphosphonium ylide

Guidance literature:

In chloroform; at 40 ℃; for 117h;

DOI:10.1081/SCC-120002015

upstream raw materials:

ethanol

1,2,4-benzene tricarboxylic acid

propynoic acid ethyl ester

bicyclo[2.2.1]hepta-2,5-diene

Refernces

• 1、 Yong, Li,Kirleis, Karin,Butenschoen, Holger. "Stereodivergent formation of alkenylsilanes: syn or anti Hydrosilylation of alkynes catalyzed by a cyclopentadienylcobalt(I) chelate bearing a pendant phosphane tether". . p. 833 - 836. Retrieved 2006.
• 2、 Evans et al.. "". . p. 295,306,312. Retrieved 1974.
• 3、 Doll, Julianna S.,Eichelmann, Robert,Hertwig, Leif E.,Bender, Thilo,Kohler, Vincenz J.,Bill, Eckhard,Wadepohl, Hubert,Ro?ca, Drago?-Adrian. "Iron-catalyzed trimerization of terminal alkynes enabled by pyrimidinediimine ligands: A regioselective method for the synthesis of 1,3,5-substituted arenes". . p. 5593 - 5600. Retrieved 2021/05/31.
• 4、 Orsino, Alessio F.,Gutiérrez Del Campo, Manuel,Lutz, Martin,Moret, Marc-Etienne. "Enhanced Catalytic Activity of Nickel Complexes of an Adaptive Diphosphine-Benzophenone Ligand in Alkyne Cyclotrimerization". . p. 2458 - 2481. Retrieved 2019/03/08.