Triethyl 1,3,5-benzenetricarboxylate

Base Information

• Chemical Name: Triethyl 1,3,5-benzenetricarboxylate
• CAS No.: 4105-92-4
• Molecular Formula: C15H18 O6
• Molecular Weight: 294.304
• Hs Code.: 2917399090
• Mol file: 4105-92-4.mol

Synonyms:1,3,5-Benzenetricarboxylicacid, triethyl ester (7CI,8CI,9CI); Trimesic acid triethyl ester (6CI);1,3,5-Tri(carboethoxy)benzene; 1,3,5-Tri(ethoxycarbonyl)benzene;1,3,5-Tricarbethoxybenzene; 1,3,5-Tris(ethoxycarbonyl)benzene; NSC 17517;Triethyl 1,3,5-benzenetricarboxylate; Triethyl trimesate

Chemical Property of Triethyl 1,3,5-benzenetricarboxylate

Chemical Property:

• Vapor Pressure: 3.68E-06mmHg at 25°C
• Melting Point: 134-139 ºC
• Boiling Point: 385.9°C at 760 mmHg
• Flash Point: 168.4°C
• PSA: 78.90000
• Density: 1.164g/cm³
• LogP: 2.21670
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

TriethylBenzene-1,3,5-tricarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Triethyl 1,3,5-benzenetricarboxylate

There total 94 articles about Triethyl 1,3,5-benzenetricarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethanol (64-17-5) + benzene-1,3,5-tricarboxylic acid (554-95-0) → triethyl benzene-1,3,5-tricarboxylate (4105-92-4)

Guidance literature:

With hydrogenchloride; Heating;

Reference yield: 99.1%

propynoic acid ethyl ester (623-47-2) → triethyl benzene-1,3,5-tricarboxylate (4105-92-4)

Guidance literature:

With chloro-trimethyl-silane; In butan-1-ol; benzene; at 40 ℃; for 8h; regioselective reaction;

DOI:10.1166/jnn.2011.4173

Reference yield: 92.0%

propynoic acid ethyl ester (623-47-2) → triethyl benzene-1,3,5-tricarboxylate (4105-92-4) + triethyl benzene-1,2,4-tricarboxylate (14230-18-3)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; triphenylphosphine; In toluene; at 23 ℃; for 2h; Inert atmosphere;

upstream raw materials:

2-iodo-propane

ethanol

sodio-1,1,3,3-tetracarboethoxypropene

diethyl ether

Downstream raw materials:

diethyl 5-(hydroxymethyl)isophthalate

cis,cis-1,3,5-tris(hydroxymethyl)cyclohexane

cis-1,3,5-cyclohexane tricarboxylic acid

1,3,5-tris-bromomethyl-cyclohexane

Refernces

• 1、 Tamaso, Ken-Ichi,Hatamoto, Yuji,Sakaguchi, Satoshi,Obora, Yasushi,Ishii, Yasutaka. "Trisannelation of acrylates to 1,3,5-benzenetricarboxylates by a Pd(OAc)2/HPMoV/CeCl3/O2 system". . p. 3603 - 3605. Retrieved 2007.
• 2、 Doll, Julianna S.,Eichelmann, Robert,Hertwig, Leif E.,Bender, Thilo,Kohler, Vincenz J.,Bill, Eckhard,Wadepohl, Hubert,Ro?ca, Drago?-Adrian. "Iron-catalyzed trimerization of terminal alkynes enabled by pyrimidinediimine ligands: A regioselective method for the synthesis of 1,3,5-substituted arenes". . p. 5593 - 5600. Retrieved 2021/05/31.
• 3、 Orsino, Alessio F.,Gutiérrez Del Campo, Manuel,Lutz, Martin,Moret, Marc-Etienne. "Enhanced Catalytic Activity of Nickel Complexes of an Adaptive Diphosphine-Benzophenone Ligand in Alkyne Cyclotrimerization". . p. 2458 - 2481. Retrieved 2019/03/08.