BENZOIC ACID, 2-[(2-CARBOXYPHENYL)AMINO]-4-CHLORO-, DISODIUM SALT

Base Information

• Chemical Name: BENZOIC ACID, 2-[(2-CARBOXYPHENYL)AMINO]-4-CHLORO-, DISODIUM SALT
• CAS No.: 64808-48-6
• Molecular Formula: C14H10 Cl N O4 . 2 Na
• Molecular Weight: 335.654
• Hs Code.: 2942000000
• Mol file: 64808-48-6.mol

Synonyms:Benzoicacid, 2-[(2-carboxyphenyl)amino]-4-chloro-, disodium salt (9CI); CCA; Carfenil;Disodium N-(2-carboxyphenyl)-4-chloroanthranilic acid; Lobenzarit disodium;Lobenzarit disodium salt; Lobenzarit sodium

Chemical Property of BENZOIC ACID, 2-[(2-CARBOXYPHENYL)AMINO]-4-CHLORO-, DISODIUM SALT

Chemical Property:

• Vapor Pressure: 4.62E-10mmHg at 25°C
• Melting Point: 388° (dec)
• Boiling Point: 481°C at 760 mmHg
• Flash Point: 244.7°C
• PSA: 92.29000
• LogP: 0.88360
• Water Solubility.: Soluble in water

Purity/Quality:

98%,99%, ^*data from raw suppliers

LobenzaritDisodium ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: Lobenzarit sodium i s a n antiinflammatory agent useful in the treatment of rheumatoid arthritis, especially that of recent onset. Although structurally related to meclofenamic and mefenamic acids, its antiinflammatory profile is reported to be more immunomodulating in character.
• Uses: Antirheumatic.

Technology Process of BENZOIC ACID, 2-[(2-CARBOXYPHENYL)AMINO]-4-CHLORO-, DISODIUM SALT

There total 1 articles about BENZOIC ACID, 2-[(2-CARBOXYPHENYL)AMINO]-4-CHLORO-, DISODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + lobenzarit (63329-53-3) → Carfenil (64808-48-6)

Guidance literature:

In sodium hydroxide; water;

Reference yield: 95.0%

Carfenil (64808-48-6) → [4-chloro-2-(2-hydroxymethyl-phenylamino)-phenyl]-methanol (146664-23-5)

Guidance literature:

With hydrogenchloride; borane-THF; water; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.3987/COM-04-10249

upstream raw materials:

ethanol

lobenzarit

Downstream raw materials:

[4-chloro-2-(2-hydroxymethyl-phenylamino)-phenyl]-methanol

Refernces