1,4,7,10,13-Pentaazacyclohexadecane-14,16-dione, 15-(phenylmethyl)-

Base Information

• Chemical Name: 1,4,7,10,13-Pentaazacyclohexadecane-14,16-dione, 15-(phenylmethyl)-
• CAS No.: 91327-99-0
• Molecular Formula: C₁₈H₂₉N₅O₂
• Molecular Weight: 347.461
• Mol file: 91327-99-0.mol

Synonyms:

Chemical Property of 1,4,7,10,13-Pentaazacyclohexadecane-14,16-dione, 15-(phenylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4,7,10,13-Pentaazacyclohexadecane-14,16-dione, 15-(phenylmethyl)-

There total 1 articles about 1,4,7,10,13-Pentaazacyclohexadecane-14,16-dione, 15-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzyl-malonic acid dimethyl ester (49769-78-0) + N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine (112-57-2) → 15-benzyl-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione (91327-99-0)

Guidance literature:

In methanol; for 504h; Heating;

DOI:10.1021/ja00331a018

Reference yield: 43.0%

nickel(II) chloride hexahydrate + 15-benzyl-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione (91327-99-0) → [nickel(III)(H(-2)-15-benzyl-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione)H2O]ClO4*2H2O

Guidance literature:

With HClO₄; In water; Electrolysis; (N2); compounds are dissolved in deaerated water, solid NaOH is added, the purple soln. turns red and is stirred for 30 min at 25°C, electrolysis for 30 min; addn. of HClO4, pptn. of brown crystals, filtn. in air, recrystn. from water, elem. anal.;

Reference yield:

15-benzyl-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione (91327-99-0) + nickel dichloride (83864-14-6) → (COCH(CH2C6H5)CON(CH2CH2NH)3CH2CH2N)Ni (80389-72-6)

Guidance literature:

In water; NiCl2 was mixed with the ligand (5-10% excess) in borate buffer (pH 9.4) under Ar; not isolated from the soln.; UV spectral data;

DOI:10.1021/ja00331a018

upstream raw materials:

2-benzyl-malonic acid dimethyl ester

N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine

Downstream raw materials:

Ni(15-benzyl-1,4,7,10,13-pentaazacyclohexadecane-14,16-dione)(O₂)

(COCH(CH₂C₆H₅)CON(CH₂CH₂NH)3CH₂CH₂N)Ni

Refernces